Browsing by Subject "Histocompatibility Testing"
Now showing items 1-9 of 9
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Allele-level HLA matching for umbilical cord blood transplantation for non-malignant diseases in children: a retrospective analysis.
(The Lancet. Haematology, 2017-07)<h4>Background</h4>The standard for selecting unrelated umbilical cord blood units for transplantation for non-malignant diseases relies on antigen-level (lower resolution) HLA typing for HLA-A and HLA-B, and allele-level ... -
Hematopoietic cell transplantation with cord blood for cure of HIV infections.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013-03)Hematopoietic cell transplantation (HCT) using CCR5-Δ32/Δ32 stem cells from an adult donor has resulted in the only known cure of human immunodeficiency virus (HIV) infection. However, it is not feasible to repeat this procedure ... -
Lung Transplantation and the Era of the Sensitized Patient.
(Frontiers in immunology, 2021-01)Long term outcomes in lung transplant are limited by the development of chronic lung allograft dysfunction (CLAD). Within the past several decades, antibody-mediated rejection (AMR) has been recognized as a risk factor for ... -
Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012-09)The curative potential of hematopoietic stem cell transplantation in patients with chronic granulomatous disease depends on availability of a suitable donor, successful donor engraftment, and maintenance of long-term donor ... -
One-unit versus two-unit cord-blood transplantation for hematologic cancers.
(The New England journal of medicine, 2014-10)<h4>Background</h4>Umbilical-cord blood has been used as the source of hematopoietic stem cells in an estimated 30,000 transplants. The limited number of hematopoietic cells in a single cord-blood unit prevents its use in ... -
Outcomes of transplantation using various hematopoietic cell sources in children with Hurler syndrome after myeloablative conditioning.
(Blood, 2013-05)We report transplantation outcomes of 258 children with Hurler syndrome (HS) after a myeloablative conditioning regimen from 1995 to 2007. Median age at transplant was 16.7 months and median follow-up was 57 months. The ... -
Relationship of race/ethnicity and survival after single umbilical cord blood transplantation for adults and children with leukemia and myelodysplastic syndromes.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012-06)The relationship of race/ethnicity with outcomes of umbilical cord blood transplantation (UCBT) is not well known. We analyzed the association between race/ethnicity and outcomes of unrelated single UCBT for leukemia and ... -
To Match or Not to Match in Cord Blood Transplantation: A Modern Look at a Recurring Question.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2016-03) -
Umbilical cord blood transplantation for children with thalassemia and sickle cell disease.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2011-09)We examined the efficacy of unrelated cord blood (CB) transplantation in children with thalassemia (n = 35) and sickle cell disease (n = 16), using data reported to 3 registries. Donor-recipient pairs were matched at HLA-A ...
