Browsing by Subject "Hydrogen-Ion Concentration"
Now showing items 1-20 of 21
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Acid-base and electrochemical properties of manganese meso(ortho- and meta-N-ethylpyridyl)porphyrins: potentiometric, spectrophotometric and spectroelectrochemical study of protolytic and redox equilibria.
(Dalton Trans, 2010-12-28)The difference in electrostatics and reduction potentials between manganese ortho-tetrakis(N-ethylpyridinium-2-yl)porphyrin (MnTE-2-PyP) and manganese meta-tetrakis(N-ethylpyridinium-3-yl)porphyrin (MnTE-3-PyP) is a challenging ... -
Continuous shear stress alters metabolism, mass-transport, and growth in electroactive biofilms independent of surface substrate transport.
(Scientific reports, 2019-02)Electroactive bacteria such as Geobacter sulfurreducens and Shewanella onedensis produce electrical current during their respiration; this has been exploited in bioelectrochemical systems. These bacteria form thicker biofilms ... -
Cyclosporine A inhibits Ca2+-dependent stimulation of the Na+/H+ antiport in human T cells.
(J Cell Biol, 1986-08)The cyclic undecapeptide cyclosporine A (CsA) is a potent immunosuppressive agent that inhibits the initial activation of T lymphocytes. This agent appears to be most effective in blocking the action of mitogens such as ... -
Deposition of silver nanoparticles in geochemically heterogeneous porous media: predicting affinity from surface composition analysis.
(2011)The transport of uncoated silver nanoparticles (AgNPs) in a porous medium composed of silica glass beads modified with a partial coverage of iron oxide (hematite) was studied and compared to that in a porous medium composed ... -
Differential coordination demands in Fe versus Mn water-soluble cationic metalloporphyrins translate into remarkably different aqueous redox chemistry and biology.
(Inorganic chemistry, 2013-05-06)The different biological behavior of cationic Fe and Mn pyridylporphyrins in Escherichia coli and mouse studies prompted us to revisit and compare their chemistry. For that purpose, the series of ortho and meta isomers of ... -
Electrostatic Energetics of Bacillus subtilis Ribonuclease P Protein Determined by Nuclear Magnetic Resonance-Based Histidine pKa Measurements.
(Biochemistry, 2015-09-08)The pKa values of ionizable groups in proteins report the free energy of site-specific proton binding and provide a direct means of studying pH-dependent stability. We measured histidine pKa values (H3, H22, and H105) in ... -
Environmental Impacts of the Coal Ash Spill in Kingston, Tennessee: An 18-Month Survey
(2010)An 18 month investigation of the environmental impacts of the Tennessee Valley Authority (TVA) coal ash spill in Kingston, Tennessee combined with leaching experiments on the spilled TVA coal ash have revealed that leachable ... -
EPR spectroscopy of nitrite complexes of methemoglobin.
(Inorg Chem, 2010-07-19)The chemical interplay of nitrogen oxides (NO's) with hemoglobin (Hb) has attracted considerable recent attention because of its potential significance in the mechanism of NO-related vasoactivity regulated by Hb. An important ... -
Identification and inhibitory properties of a novel Ca(2+)/calmodulin antagonist.
(Biochemistry, 2010-05-18)We developed a high-throughput yeast-based assay to screen for chemical inhibitors of Ca(2+)/calmodulin-dependent kinase pathways. After screening two small libraries, we identified the novel antagonist 125-C9, a substituted ... -
Iron oxide/manganese oxide co-loaded hybrid nanogels as pH-responsive magnetic resonance contrast agents.
(Biomaterials, 2015-01)This work described a proof of concept study of hybrid nanogel-based magnetic resonance contrast agents, SPIO@GCS/acryl/biotin@Mn-gel, abb. as SGM, for highly efficient, pH-responsive T1 and T2 dual-mode magnetic resonance ... -
Magnetic resonance water proton relaxation in protein solutions and tissue: T(1rho) dispersion characterization.
(PLoS One, 2010-01-05)BACKGROUND: Image contrast in clinical MRI is often determined by differences in tissue water proton relaxation behavior. However, many aspects of water proton relaxation in complex biological media, such as protein solutions ... -
Novel hybrid action of GABA mediates inhibitory feedback in the mammalian retina.
(PLoS biology, 2019-04)The stream of visual information sent from photoreceptors to second-order bipolar cells is intercepted by laterally interacting horizontal cells that generate feedback to optimize and improve the efficiency of signal ... -
Overexpression of the cardiac beta(2)-adrenergic receptor and expression of a beta-adrenergic receptor kinase-1 (betaARK1) inhibitor both increase myocardial contractility but have differential effects on susceptibility to ischemic injury.
(Circ Res, 1999-11-26)Cardiac beta(2)-adrenergic receptor (beta(2)AR) overexpression is a potential contractile therapy for heart failure. Cardiac contractility was elevated in mice overexpressing beta(2)ARs (TG4s) with no adverse effects under ... -
Potential impacts of leakage from deep CO2 geosequestration on overlying freshwater aquifers.
(Environ Sci Technol, 2010-12-01)Carbon Capture and Storage may use deep saline aquifers for CO(2) sequestration, but small CO(2) leakage could pose a risk to overlying fresh groundwater. We performed laboratory incubations of CO(2) infiltration under oxidizing ... -
Potential involvement of intracellular pH in a mouse model of amyotrophic lateral sclerosis.
(Amyotrophic lateral sclerosis & frontotemporal degeneration, 2014-03) -
Protein purification: adsorption chromatography on controlled pore glass with the use of chaotropic buffers.
(Science (New York, N.Y.), 1976-01)Chromatography on controlled pore glass in combination with chaotropic buffers makes possible, in a single step, protein purifications of several hundredfold. The new emphasis is on highly selective controllable adsorption. ... -
Quantitative model of the phase behavior of recombinant pH-responsive elastin-like polypeptides.
(Biomacromolecules, 2010-11-08)Quantitative models are required to engineer biomaterials with environmentally responsive properties. With this goal in mind, we developed a model that describes the pH-dependent phase behavior of a class of stimulus responsive ... -
Radium and barium removal through blending hydraulic fracturing fluids with acid mine drainage.
(Environ Sci Technol, 2014-01-21)Wastewaters generated during hydraulic fracturing of the Marcellus Shale typically contain high concentrations of salts, naturally occurring radioactive material (NORM), and metals, such as barium, that pose environmental ... -
Rapid in vitro assembly of Caulobacter crescentus FtsZ protein at pH 6.5 and 7.2.
(The Journal of biological chemistry, 2013-08)FtsZ from most bacteria assembles rapidly in vitro, reaching a steady-state plateau in 5-10 s after addition of GTP. A recent study used a novel dynamic light-scattering technique to assay the assembly of FtsZ from Caulobacter ... -
Safety profile of L-arginine infusion in moderately severe falciparum malaria.
(PLoS One, 2008-06-11)BACKGROUND: L-arginine infusion improves endothelial function in malaria but its safety profile has not been described in detail. We assessed clinical symptoms, hemodynamic status and biochemical parameters before and after ...
