Browsing by Subject "Immunocompromised Host"
Now showing items 1-8 of 8
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Chronic coinfections in patients diagnosed with chronic lyme disease: a systematic review.
(Am J Med, 2014-11)PURPOSE: Often, the controversial diagnosis of chronic Lyme disease is given to patients with prolonged, medically unexplained physical symptoms. Many such patients also are treated for chronic coinfections with Babesia, ... -
Histopathologic assessment of cultured human thymus.
(PloS one, 2020-01)The maintenance and propagation of complex mixtures of cells in vitro in the form of native organs or engineered organoids has contributed to understanding mechanisms of cell and organ development and function which can ... -
Host-Based Diagnostics for Acute Respiratory Infections.
(Clinical therapeutics, 2019-10)PURPOSE:The inappropriate use of antimicrobials, especially in acute respiratory infections (ARIs), is largely driven by difficulty distinguishing bacterial, viral, and noninfectious etiologies of illness. A new frontier ... -
Invasive Curvularia Infection in Pediatric Patients With Hematologic Malignancy Identified by Fungal Sequencing.
(Journal of the Pediatric Infectious Diseases Society, 2019-03)Curvularia is a saprophytic dematiaceous mold and a rare human pathogen. Here, we report three severely immunocompromised pediatric patients who developed invasive Curvularia infection. Diagnosis was achieved or confirmed ... -
Invasive fungal infections among organ transplant recipients: results of the Transplant-Associated Infection Surveillance Network (TRANSNET).
(Clin Infect Dis, 2010-04-15)BACKGROUND: Invasive fungal infections (IFIs) are a major cause of morbidity and mortality among organ transplant recipients. Multicenter prospective surveillance data to determine disease burden and secular trends are lacking. ... -
Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001-2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database.
(Clin Infect Dis, 2010-04-15)BACKGROUND: The incidence and epidemiology of invasive fungal infections (IFIs), a leading cause of death among hematopoeitic stem cell transplant (HSCT) recipients, are derived mainly from single-institution retrospective ... -
Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012-05)No therapeutic agent has yet been established as the definitive therapy for adenovirus infections. We describe the clinical experience of 13 immunocompromised patients who received CMX001 (hexadecyloxypropyl cidofovir), ... -
Validation of a Host Gene Expression Test for Bacterial/Viral Discrimination in Immunocompromised Hosts.
(Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021-08)<h4>Background</h4>Host gene expression has emerged as a complementary strategy to pathogen detection tests for the discrimination of bacterial and viral infection. The impact of immunocompromise on host-response tests remains ...