Now showing items 1-3 of 3

    • Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines. 

      Alam, S Munir; Barbero, G; Chang, C; Chen, PP; Denny, Thomas Norton; Drinker, MS; Edmonds, TG; ... (28 authors) (J Exp Med, 2010-04-12)
      Traditional antibody-mediated neutralization of HIV-1 infection is thought to result from the binding of antibodies to virions, thus preventing virus entry. However, antibodies that broadly neutralize HIV-1 are rare and ...
    • Interleukin-15 receptor blockade in non-human primate kidney transplantation. 

      Faure, JP; Fechner, J; Haustein, S; Kayaoglu, A; Knechtle, Stuart J; Kwun, J; Roenneburg, D; ... (8 authors) (Transplantation, 2010-04-27)
      BACKGROUND: Interleukin (IL)-15 is a chemotactic factor to T cells. It induces proliferation and promotes survival of activated T cells. IL-15 receptor blockade in mouse cardiac and islet allotransplant models has led to ...
    • Suppression of conformational heterogeneity at a protein-protein interface. 

      Daniels, Kyle G; Deis, LN; Oas, Terrence Gilbert; Qi, Y; Wang, Y; Wu, Q; Zhou, Pei (Proc Natl Acad Sci U S A, 2015-07-21)
      Staphylococcal protein A (SpA) is an important virulence factor from Staphylococcus aureus responsible for the bacterium's evasion of the host immune system. SpA includes five small three-helix-bundle domains that can each ...