ALERT: This system is being upgraded on Tuesday December 12. It will not be available
for use for several hours that day while the upgrade is in progress. Deposits to DukeSpace
will be disabled on Monday December 11, so no new items are to be added to the repository
while the upgrade is in progress. Everything should be back to normal by the end of
day, December 12.
Browsing by Subject "Infant, Newborn"
Now showing items 1-20 of 104
-
A Longitudinal Cohort Study of Malaria Exposure and Changing Serostatus in a Malaria Endemic Area of Rural Tanzania
(Malaria Journal, 2017-08-02)<h4>Background</h4>Measurements of anti-malarial antibodies are increasingly used as a proxy of transmission intensity. Most serological surveys are based on the use of cross-sectional data that, when age-stratified, approximates ... -
A prospective neurosurgical registry evaluating the clinical care of traumatic brain injury patients presenting to Mulago National Referral Hospital in Uganda.
(PloS one, 2017-01)<h4>Background</h4>Traumatic Brain Injury (TBI) is disproportionally concentrated in low- and middle-income countries (LMICs), with the odds of dying from TBI in Uganda more than 4 times higher than in high income countries ... -
A risk factor analysis of outcomes after unrelated cord blood transplantation for children with Wiskott-Aldrich syndrome.
(Haematologica, 2017-06)Wiskott-Aldrich syndrome is a severe X-linked recessive immune deficiency disorder. A scoring system of Wiskott-Aldrich syndrome severity (0.5-5) distinguishes two phenotypes: X-linked thrombocytopenia and classic Wiskott-Aldrich ... -
Abnormal oxidative stress responses in fibroblasts from preeclampsia infants.
(PloS one, 2014-01)<h4>Background</h4>Signs of severe oxidative stress are evident in term placentae of infants born to mothers with preeclampsia (PE), but it is unclear whether this is a cause or consequence of the disease. Here fibroblast ... -
Algorithm for the early diagnosis and treatment of patients with cross reactive immunologic material-negative classic infantile pompe disease: a step towards improving the efficacy of ERT.
(PLoS One, 2013)OBJECTIVE: Although enzyme replacement therapy (ERT) is a highly effective therapy, CRIM-negative (CN) infantile Pompe disease (IPD) patients typically mount a strong immune response which abrogates the efficacy of ERT, ... -
Analyses of pediatric isolates of Cryptococcus neoformans from South Africa.
(J Clin Microbiol, 2011-01)Compared to the incidence in adults, cryptococcosis is inexplicably rare among children, even in sub-Saharan Africa, which has the highest prevalence of coinfection with HIV and Cryptococcus neoformans. To explore any mycological ... -
Analysis of educational materials and destruction/opt-out initiatives for storage and use of residual newborn screening samples.
(Genet Test Mol Biomarkers, 2010-10)In recent years, the storage and use of residual newborn screening (NBS) samples has gained attention. To inform ongoing policy discussions, this article provides an update of previous work on new policies, educational materials, ... -
Anomalous Origin of the Right Coronary Artery from the Pulmonary Artery in a Neonate with Turner Syndrome and Aortic Arch Hypoplasia.
(Texas Heart Institute journal, 2019-06)Anomalous origin of the right coronary artery from the pulmonary artery, a rare congenital cardiac defect, is typically not diagnosed during infancy. On the other hand, Turner syndrome is usually diagnosed early, and it ... -
Application of the estrogen threshold hypothesis to the physiologic hypoestrogenemia of lactation.
(Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, 2015-03)OBJECTIVE: This study determined the impact of breastfeeding on hypoestrogenic symptoms among women in the postpartum period and correlated these findings with the Estrogen Threshold Hypothesis, which postulates that the ... -
Assessing risk of breast cancer in an ethnically South-East Asia population (results of a multiple ethnic groups study).
(BMC cancer, 2012-11-19)<h4>Background</h4>Gail and others developed a model (GAIL) using age-at-menarche, age-at-birth of first live child, number of previous benign breast biopsy examinations, and number of first-degree-relatives with breast ... -
Association of cord blood methylation fractions at imprinted insulin-like growth factor 2 (IGF2), plasma IGF2, and birth weight.
(Cancer causes & control : CCC, 2012-04)<h4>Purpose</h4>Altered methylation at Insulin-like Growth Factor 2 (IGF2) regulatory regions has previously been associated with obesity, and several malignancies including colon, esophageal, and prostate adenocarcinomas, ... -
Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
(J Virol, 2015-10)UNLABELLED: Infants born to HIV-1-infected mothers in resource-limited areas where replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding. Despite this, the majority of infants ... -
Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring.
(International journal of obesity (2005), 2013-07)<h4>Objectives</h4>Low birth weight (LBW) has been associated with common adult-onset chronic diseases, including obesity, cardiovascular disease, type II diabetes and some cancers. The etiology of LBW is multi-factorial. ... -
Behavior genetics and postgenomics.
(Behav Brain Sci, 2012-10)The science of genetics is undergoing a paradigm shift. Recent discoveries, including the activity of retrotransposons, the extent of copy number variations, somatic and chromosomal mosaicism, and the nature of the epigenome ... -
Brincidofovir for Asymptomatic Adenovirus Viremia in Pediatric and Adult Allogeneic Hematopoietic Cell Transplant Recipients: A Randomized Placebo-Controlled Phase II Trial.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2017-03)Adenovirus infection in immunocompromised patients contributes to significant morbidity and mortality, especially after allogeneic hematopoietic cell transplantation (HCT). Brincidofovir (BCV, CMX001) is an orally bioavailable ... -
Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child.
(Addiction (Abingdon, England), 2016-12)<h4>Aims</h4>To assess the safety of buprenorphine compared with methadone to treat pregnant women with opioid use disorder.<h4>Methods</h4>We searched PubMed, Embase and the Cochrane Library from inception to February 2015 ... -
Case 1: Eye Discharge in a 10-day-old Neonate Born by Cesarean Delivery.
(Pediatrics in review, 2018-04) -
Changing cancer survival in China during 2003-15: a pooled analysis of 17 population-based cancer registries.
(The Lancet. Global health, 2018-05)From 2003 to 2005, standardised 5-year cancer survival in China was much lower than in developed countries and varied substantially by geographical area. Monitoring population-level cancer survival is crucial to the understanding ... -
Changing epidemiology of serious bacterial infections in febrile infants without localizing signs.
(PLoS One, 2010-08-27)OBJECTIVE: Historically, management of infants with fever without localizing signs (FWLS) has generated much controversy, with attempts to risk stratify based on several criteria. Advances in medical practice may have altered ... -
Characteristics of abdominal vein thrombosis in children and adults.
(Thromb Haemost, 2013-04)The demographic and clinical characteristics of adults and children with lower extremity deep-vein thrombosis and/or pulmonary embolism (LE DVT/PE) may differ from those with abdominal vein thrombosis (abdominal VT). Abdominal ...
