Browsing by Subject "Inorganic chemistry"
Now showing items 1-10 of 10
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Characterizing the Physiochemical Properties of Copper Chelating Agents: an Effort Towards Understanding their Antifungal Activity
(2015)An increase in drug-resistant infections and the paucity of new antibiotics present a major world health problem. Cryptococcus neoformans (C. neoformans) is an opportunistic fungal pathogen responsible for life-threatening ... -
Evaluating the copper-binding properties of the antifungal peptide histatin 5
(2014)Histatins are a family of histidine-rich peptides that are found in saliva. This family of peptides has antifungal properties. In this family, histatin 5 is the most efficient antifungal peptide against Candida albicans. ... -
Gold(I)-Catalyzed Enantioselective Hydroamination of Unactivated Alkenes
(2012)Numerous methodologies for efficient formation of carbon-nitrogen bonds have been developed over the decades due to the widespread importance of nitrogen containing compounds in pharmaceuticals and bulk commercial chemicals. ... -
Improving Stability and Selectivity in Electrochemical Reduction of Carbon Dioxide in an Aqueous Solution
(2018)With the rising level of CO2 in the atmosphere, methods capable of converting CO2 into useful fuels are urgently needed. The electrochemical CO2 reduction has gained significant interest recently due to its ability to use ... -
Insight into the Role of Metal Homeostasis in Fungal Adaptation to Drug Stress
(2019)Maintenance of metal homeostasis is critical to cell survival due to the multitude of cellular processes that depend on one or more metal cofactors. We show that the opportunistic fungal pathogen Candida albicans becomes ... -
Leveraging Bioorthogonal Chemistry for Hyperpolarized Magnetic Resonance and Metal Uncaging
(2018)Bioorthogonal chemistry is a burgeoning area of study that has innumerable applications. This dissertation describes applications of bioorthogonal chemistry to solve problems in the fields of imaging and metal uncaging. ... -
Metal-Ligand Interactions in Stimuli Responsive Molecules
(2018)The ability to control changes in physical and chemical properties has allowed stimuli responsive molecules to be used in a variety of applications. Incorporating metals into stimuli responsive molecules introduces properties ... -
Model Studies of Proposed Intermediates in Homogeneous Gold(I) Catalysis
(2012)The ability of gold(I) complexes to function as catalysts for myriad organic transformations has led to a dramatic increase in their utilization. Among the homogeneous reactions catalyzed by gold(I), carbon-carbon ... -
Synthesis, Functionalization, and Characterization of Dominant UV Emitting Upconverting Nanocrystals and Absolute Quantum Yield and Power Dependence Metrics for the Elucidation of Upconversion Mechanisms
(2015)The discovery, formulation, and characterization of novel compositions of matter for aid in the diagnosis and treatment of disease has ever been a compelling force behind nanomaterials development. In instances of disease ... -
The Design, Synthesis and Characterization of Lanthanide-based Nanomaterials and Their Use in 3D Biological Imaging and Radiation Dosimetry
(2018)Lanthanide-doped materials have been studied for decades for their unique photophysical properties derived from their f-block orbitals. More recently, the prominence of techniques allowing for the study and characterization ...
