Browsing by Subject "Integrin alphaVbeta3"

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Morphing low-affinity ligands into high-avidity nanoparticles by thermally triggered self-assembly of a genetically encoded polymer.

Simnick, Andrew J; Valencia, C Alexander; Liu, Rihe; Chilkoti, Ashutosh (ACS Nano, 2010-04-27)

Multivalency is the increase in avidity resulting from the simultaneous interaction of multiple ligands with multiple receptors. This phenomenon, seen in antibody-antigen and virus-cell membrane interactions, is useful in ...