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    • The quantity and quality of worldwide new drug introductions, 1982-2003. 

      Grabowski, Henry G; Wang, Y Richard (Health Aff (Millwood), 2006-03)
      We examined trends in the introduction of new chemical entities (NCEs) worldwide from 1982 through 2003. Although annual introductions of NCEs decreased over time, introductions of high-quality NCEs (that is, global and ...