Now showing items 1-3 of 3

    • Earlier onset and greater severity of disordered mineral metabolism in diabetic patients with chronic kidney disease. 

      Scialla, Julia; Wolf, Myles; Wahl, Patricia; Xie, Huiliang; Anderson, Cheryl AM; Bellovich, Keith; Brecklin, Carolyn; ... (17 authors) (Diabetes care, 2012-05)
      Disordered mineral metabolism is a common complication of chronic kidney disease (CKD) and a novel risk factor for CKD progression, cardiovascular disease, and mortality. Although diabetes is the leading cause of CKD and ...
    • Experimental inhibition of porcupine-mediated Wnt O-acylation attenuates kidney fibrosis. 

      Bunte, RM; Crowley, Steven Daniel; Griffiths, Robert; Madan, B; Patel, MB; Rudemiller, Nathan P; Virshup, DM; ... (8 authors) (Kidney Int, 2016-05)
      Activated Wnt signaling is critical in the pathogenesis of renal fibrosis, a final common pathway for most forms of chronic kidney disease. Therapeutic intervention by inhibition of individual Wnts or downstream Wnt/β-catenin ...
    • Shared features in the pathobiology of babesiosis and malaria. 

      Daily, J; Krause, PJ; Lantos, Paul; Spielman, A; Telford, SR; Vannier, E (Trends Parasitol, 2007-12)
      The pathobiology of malaria has been extensively studied in humans but many questions remain, especially regarding fulminant disease associated with Plasmodium falciparum infection. Babesiosis, recognized since biblical ...