Browsing by Subject "LAT"
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The Function of LAT in T Cell Activation and Autoimmunity
(2010)LAT (linker for activation of T cells) is an important transmembrane adaptor protein in TCR-mediated signaling. Upon TCR engagement, LAT associates with multiple proteins which allows for the activation of downstream signaling ... -
The Gatekeeper of TCR Signaling: LAT in T cell Homeostasis and Autoimmunity
(2015)Linker for Activation of T cells, LAT, is a transmembrane adaptor protein that is vital for integrating TCR-mediated signals that modulate T cell development, activation, and proliferation. Upon engagement of the T cell ...
