Browsing by Subject "Longitudinal data"

Dynamics of biomarkers in relation to aging and mortality.

Arbeev, Konstantin G; Ukraintseva, Svetlana V; Yashin, Anatoliy I (Mech Ageing Dev, 2016-06)

Contemporary longitudinal studies collect repeated measurements of biomarkers allowing one to analyze their dynamics in relation to mortality, morbidity, or other health-related outcomes. Rich and diverse data collected ...

How the effects of aging and stresses of life are integrated in mortality rates: insights for genetic studies of human health and longevity.

Yashin, Anatoliy I; Arbeev, Konstantin G; Arbeeva, Liubov S; Wu, Deqing; Akushevich, Igor; Kovtun, Mikhail; Yashkin, Arseniy; ... (12 authors) (Biogerontology, 2016-02)

Increasing proportions of elderly individuals in developed countries combined with substantial increases in related medical expenditures make the improvement of the health of the elderly a high priority today. If the process ...

Statistical Analysis of Response Distribution for Dependent Data via Joint Quantile Regression

Chen, Xu (2021)

Linear quantile regression is a powerful tool to investigate how predictors may affect a response heterogeneously across different quantile levels. Unfortunately, existing approaches find it extremely difficult to adjust ...

stpm: an R package for stochastic process model.

Zhbannikov, Ilya Y; Arbeev, Konstantin; Akushevich, Igor; Stallard, Eric; Yashin, Anatoliy I (BMC Bioinformatics, 2017-02-23)

BACKGROUND: The Stochastic Process Model (SPM) represents a general framework for modeling the joint evolution of repeatedly measured variables and time-to-event outcomes observed in longitudinal studies, i.e., SPM relates ...