Browsing by Subject "MSC"

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Functional Tissue Engineering of Cartilage Using Adipose-derived Stem Cells

Estes, Bradley Thomas (2008-03-31)

Articular cartilage is the thin, load-bearing connective tissue that lines the ends of long bones in diarthroidal joints, providing predominantly a mechanical function. Because cartilage is avascular and aneural, it has ...
Single-cell RNA-seq of out-of-thaw mesenchymal stromal cells shows tissue-of-origin differences and inter-donor cell-cycle variations.

Medrano-Trochez, Camila; Chatterjee, Paramita; Pradhan, Pallab; Stevens, Hazel Y; Ogle, Molly E; Botchwey, Edward A; Kurtzberg, Joanne; ... (10 authors) (Stem cell research & therapy, 2021-11-04)

<h4>Background</h4>Human Mesenchymal stromal cells (hMSCs) from various tissue sources are widely investigated in clinical trials. These MSCs are often administered to patients immediately after thawing the cryopreserved ...