Now showing items 1-10 of 10

    • A polyaxonal amacrine cell population in the primate retina. 

      Field, Greg; Greschner, Martin; Li, Peter H; Schiff, Max L; Gauthier, Jeffrey L; Ahn, Daniel; Sher, Alexander; ... (9 authors) (The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014-03)
      Amacrine cells are the most diverse and least understood cell class in the retina. Polyaxonal amacrine cells (PACs) are a unique subset identified by multiple long axonal processes. To explore their functional properties, ...
    • Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings. 

      Ahn, D; Callaway, EM; Chichilnisky, EJ; Field, Greg; Gauthier, JL; Greschner, M; Li, PH; ... (10 authors) (J Neurosci, 2015-03-18)
      This study combines for the first time two major approaches to understanding the function and structure of neural circuits: large-scale multielectrode recordings, and confocal imaging of labeled neurons. To achieve this ...
    • Correlated firing among major ganglion cell types in primate retina. 

      Field, Greg; Greschner, Martin; Shlens, Jonathon; Bakolitsa, Constantina; Gauthier, Jeffrey L; Jepson, Lauren H; Sher, Alexander; ... (9 authors) (The Journal of physiology, 2011-01)
      Retinal ganglion cells exhibit substantial correlated firing: a tendency to fire nearly synchronously at rates different from those expected by chance. These correlations suggest that network interactions significantly shape ...
    • Dust accumulation in the canopy: a potential cause of dental microwear in primates. 

      Glander, Kenneth Earl; Pastor, RF; Teaford, Mark F; Ungar, PS (Am J Phys Anthropol, 1995-06)
      Dental microwear researchers consider exogenous grit or dust to be an important cause of microscopic wear on primate teeth. No study to date has examined the accumulation of such abrasives on foods eaten by primates in the ...
    • Functional connectivity in the retina at the resolution of photoreceptors. 

      Field, Greg; Gauthier, Jeffrey L; Sher, Alexander; Greschner, Martin; Machado, Timothy A; Jepson, Lauren H; Shlens, Jonathon; ... (13 authors) (Nature, 2010-10)
      To understand a neural circuit requires knowledge of its connectivity. Here we report measurements of functional connectivity between the input and ouput layers of the macaque retina at single-cell resolution and the implications ...
    • High-sensitivity rod photoreceptor input to the blue-yellow color opponent pathway in macaque retina. 

      Chichilnisky, EJ; Field, Greg; Gauthier, JL; Greschner, M; Litke, Alan M; Marshak, DW; Rangel, C; ... (9 authors) (Nat Neurosci, 2009-09)
      Small bistratified cells (SBCs) in the primate retina carry a major blue-yellow opponent signal to the brain. We found that SBCs also carry signals from rod photoreceptors, with the same sign as S cone input. SBCs exhibited ...
    • Identification of a Retinal Circuit for Recurrent Suppression Using Indirect Electrical Imaging. 

      Field, Greg; Greschner, Martin; Heitman, Alexander K; Li, Peter H; Ahn, Daniel; Sher, Alexander; Litke, Alan M; ... (8 authors) (Current biology : CB, 2016-08)
      Understanding the function of modulatory interneuron networks is a major challenge, because such networks typically operate over long spatial scales and involve many neurons of different types. Here, we use an indirect electrical ...
    • Interleukin-15 receptor blockade in non-human primate kidney transplantation. 

      Faure, JP; Fechner, J; Haustein, S; Kayaoglu, A; Knechtle, Stuart J; Kwun, J; Roenneburg, D; ... (8 authors) (Transplantation, 2010-04-27)
      BACKGROUND: Interleukin (IL)-15 is a chemotactic factor to T cells. It induces proliferation and promotes survival of activated T cells. IL-15 receptor blockade in mouse cardiac and islet allotransplant models has led to ...
    • Monte Carlo methods for localization of cones given multielectrode retinal ganglion cell recordings. 

      Field, Greg; Sadeghi, K; Gauthier, JL; Greschner, M; Agne, M; Chichilnisky, EJ; Paninski, L (Network (Bristol, England), 2013-01)
      It has recently become possible to identify cone photoreceptors in primate retina from multi-electrode recordings of ganglion cell spiking driven by visual stimuli of sufficiently high spatial resolution. In this paper we ...
    • Prevention trumps treatment of antibody-mediated transplant rejection. 

      Iwakoshi, Neal N; Knechtle, Stuart J; Kwun, J (J Clin Invest, 2010-04)
      Belying the spectacular success of solid organ transplantation and improvements in immunosuppressive therapy is the reality that long-term graft survival rates remain relatively unchanged, in large part due to chronic and ...