Browsing by Subject "Macaca mulatta"
Now showing items 1-20 of 71
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A pathway in primate brain for internal monitoring of movements.
(Science, 2002-05-24)It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem ... -
A polyaxonal amacrine cell population in the primate retina.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014-03)Amacrine cells are the most diverse and least understood cell class in the retina. Polyaxonal amacrine cells (PACs) are a unique subset identified by multiple long axonal processes. To explore their functional properties, ... -
A Refined Neuronal Population Measure of Visual Attention.
(PloS one, 2015-01)Neurophysiological studies of cognitive mechanisms such as visual attention typically ignore trial-by-trial variability and instead report mean differences averaged across many trials. Advances in electrophysiology allow ... -
Activity of neurons in monkey globus pallidus during oculomotor behavior compared with that in substantia nigra pars reticulata.
(J Neurophysiol, 2010-04)The basal ganglia are a subcortical assembly of nuclei involved in many aspects of behavior. Three of the nuclei have high firing rates and inhibitory influences: the substantia nigra pars reticulata (SNr), globus pallidus ... -
Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells.
(Frontiers in immunology, 2021-01)Antibody-mediated allograft rejection (AMR) causes more kidney transplant failure than any other single cause. AMR is mediated by antibodies recognizing antigens expressed by the graft, and antibodies generated against major ... -
Anatomical identification of extracellularly recorded cells in large-scale multielectrode recordings.
(J Neurosci, 2015-03-18)This study combines for the first time two major approaches to understanding the function and structure of neural circuits: large-scale multielectrode recordings, and confocal imaging of labeled neurons. To achieve this ... -
Auditory signals evolve from hybrid- to eye-centered coordinates in the primate superior colliculus.
(Journal of neurophysiology, 2012-07)Visual and auditory spatial signals initially arise in different reference frames. It has been postulated that auditory signals are translated from a head-centered to an eye-centered frame of reference compatible with the ... -
Coherence potentials: loss-less, all-or-none network events in the cortex.
(PLoS Biol, 2010-01-12)Transient associations among neurons are thought to underlie memory and behavior. However, little is known about how such associations occur or how they can be identified. Here we recorded ongoing local field potential (LFP) ... -
Compensatory saccades made to remembered targets following orbital displacement by electrically stimulating the dorsomedial frontal cortex or frontal eye fields of primates.
(Brain Res, 1996-07-15)If the eye-position signal during visually-evoked saccades is dependent on the dorsomedial frontal cortex (DMFC), one would expect that saccades generated to briefly presented visual targets would be disrupted after displacement ... -
Composition and topographic organization of signals sent from the frontal eye field to the superior colliculus.
(J Neurophysiol, 2000-04)The frontal eye field (FEF) and superior colliculus (SC) contribute to saccadic eye movement generation, and much of the FEF's oculomotor influence may be mediated through the SC. The present study examined the composition ... -
Correlated firing among major ganglion cell types in primate retina.
(The Journal of physiology, 2011-01)Retinal ganglion cells exhibit substantial correlated firing: a tendency to fire nearly synchronously at rates different from those expected by chance. These correlations suggest that network interactions significantly shape ... -
Costimulation blockade alters germinal center responses and prevents antibody-mediated rejection.
(Am J Transplant, 2014-01)De novo donor-specific antibody (DSA) after organ transplantation promotes antibody-mediated rejection (AMR) and causes late graft loss. Previously, we demonstrated that depletion using anti-CD3 immunotoxin combined with ... -
Delay activity of saccade-related neurons in the caudal dentate nucleus of the macaque cerebellum.
(J Neurophysiol, 2013-04)The caudal dentate nucleus (DN) in lateral cerebellum is connected with two visual/oculomotor areas of the cerebrum: the frontal eye field and lateral intraparietal cortex. Many neurons in frontal eye field and ... -
Delineation and Modulation of the Natural Killer Cell Transcriptome in Rhesus Macaques During ZIKV and SIV Infections.
(Frontiers in cellular and infection microbiology, 2020-01)Natural killer (NK) cells are crucial regulators of antiviral and anti-tumor immune responses. Although in humans some NK cell transcriptional programs are relatively well-established, NK cell transcriptional networks in ... -
Division of labor in frontal eye field neurons during presaccadic remapping of visual receptive fields.
(J Neurophysiol, 2012-10)Our percept of visual stability across saccadic eye movements may be mediated by presaccadic remapping. Just before a saccade, neurons that remap become visually responsive at a future field (FF), which anticipates the saccade ... -
Dynamics of visual receptive fields in the macaque frontal eye field.
(J Neurophysiol, 2015-12)Neuronal receptive fields (RFs) provide the foundation for understanding systems-level sensory processing. In early visual areas, investigators have mapped RFs in detail using stochastic stimuli and sophisticated analytical ... -
Effective spread and timecourse of neural inactivation caused by lidocaine injection in monkey cerebral cortex.
(J Neurosci Methods, 1997-06-06)We studied the effective spread of lidocaine to inactivate neural tissue in the frontal cortex of the rhesus monkey. Injections of 2% lidocaine at 4 microl/min were made while units were recorded 1 or 2 mm away. To inactivate ... -
Effects of Electrical Stimulation in the Inferior Colliculus on Frequency Discrimination by Rhesus Monkeys and Implications for the Auditory Midbrain Implant.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016-05)Understanding the relationship between the auditory selectivity of neurons and their contribution to perception is critical to the design of effective auditory brain prosthetics. These prosthetics seek to mimic natural activity ... -
Efficient coding of spatial information in the primate retina.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012-11)Sensory neurons have been hypothesized to efficiently encode signals from the natural environment subject to resource constraints. The predictions of this efficient coding hypothesis regarding the spatial filtering properties ... -
Electrically evoked saccades from the dorsomedial frontal cortex and frontal eye fields: a parametric evaluation reveals differences between areas.
(Exp Brain Res, 1997-12)Using electrical stimulation to evoke saccades from the dorsomedial frontal cortex (DMFC) and frontal eye fields (FEF) of rhesus monkeys, parametric tests were conducted to compare the excitability properties of these regions. ...
