Browsing by Subject "Male"
Now showing items 1-20 of 1063
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3-[211At]astato-4-fluorobenzylguanidine: a potential therapeutic agent with prolonged retention by neuroblastoma cells.
(Br J Cancer, 1997)An analogue of meta-iodobenzylguanidine (MIBG) in which an aromatic hydrogen was replaced with fluorine has been found to possess many properties similar to those of the parent compound. Moreover, 4-fluoro-3-iodobenzylguanidine ... -
5-α reductase inhibitors and prostate cancer prevention: where do we turn now?
(BMC Med, 2011-09-15)With the lifetime risk of being diagnosed with prostate cancer so great, an effective chemopreventive agent could have a profound impact on the lives of men. Despite decades of searching for such an agent, physicians still ... -
A case of frontal neuropsychological and neuroimaging signs following multiple primary-blast exposure.
(Neurocase, 2012-06)Blast-related traumatic brain injury (TBI) from the Afghanistan and Iraq wars represents a significant medical concern for troops and veterans. To better understand the consequences of primary-blast injury in humans, we ... -
A case-control study of airways obstruction among construction workers.
(Am J Ind Med, 2015-10)BACKGROUND: While smoking is the major cause of chronic obstructive pulmonary disease (COPD), occupational exposures to vapors, gases, dusts, and fumes (VGDF) increase COPD risk. This case-control study estimated the risk ... -
A cohort study of 4,190 patients treated with low-intensity pulsed ultrasound (LIPUS): findings in the elderly versus all patients.
(BMC Musculoskelet Disord, 2015-03-01)BACKGROUND: Patient age is one of many potential risk factors for fracture nonunion. Our hypothesis is that older patients (≥ 60) with fracture risk factors treated with low-intensity pulsed ultrasound (LIPUS) have similar ... -
A community-based intervention increases physical activity and reduces obesity in school-age children in North Carolina.
(Child Obes, 2015-06)BACKGROUND: Community-based interventions are promising approaches to obesity prevention, but few studies have prospectively evaluated them. The aim of this study was to evaluate a natural experiment—a community intervention ... -
A comparison of activity patterns for captive Propithecus tattersalli and Propithecus coquereli.
(Zoo Biol, 2016-03)The activity patterns and social interactions of two species of captive sifaka were observed during a 2-year period. Allogrooming was not observed in golden-crowned sifaka and they spent significantly more time resting than ... -
A comparison of dimensional models of emotion: evidence from emotions, prototypical events, autobiographical memories, and words.
(Memory, 2009-11)The intensity and valence of 30 emotion terms, 30 events typical of those emotions, and 30 autobiographical memories cued by those emotions were each rated by different groups of 40 undergraduates. A vector model gave a ... -
A comparison of temperament in nonhuman apes and human infants.
(Dev Sci, 2011-11)The adaptive behavior of primates, including humans, is often mediated by temperament. Human behavior likely differs from that of other primates in part due to temperament. In the current study we compared the reaction of ... -
A coprological survey of parasites of wild mantled howling monkeys, Alouatta palliata palliata.
(J Wildl Dis, 1990-10)Fecal samples from 155 mantled howling monkeys (Alouatta palliata palliata) examined at Centro Ecologico La Pacifica, Guanacaste Province, Costa Rica, revealed 75 (48%) had parasitic infections. A sampling of nine howling ... -
A craniofacial-specific monosynaptic circuit enables heightened affective pain.
(Nature neuroscience, 2017-12)Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in the face than in the body. However, the underlying neural circuitry for ... -
A cross-site, comparative effectiveness study of an integrated HIV and substance use treatment program.
(AIDS Patient Care STDS, 2010-10)Co-occurrence of HIV and substance abuse is associated with poor outcomes for HIV-related health and substance use. Integration of substance use and medical care holds promise for HIV patients, yet few integrated treatment ... -
A Diffusion MRI Tractography Connectome of the Mouse Brain and Comparison with Neuronal Tracer Data.
(Cereb Cortex, 2015-11)Interest in structural brain connectivity has grown with the understanding that abnormal neural connections may play a role in neurologic and psychiatric diseases. Small animal connectivity mapping techniques are particularly ... -
A fruit in the hand or two in the bush? Divergent risk preferences in chimpanzees and bonobos.
(Biol Lett, 2008-06-23)Human and non-human animals tend to avoid risky prospects. If such patterns of economic choice are adaptive, risk preferences should reflect the typical decision-making environments faced by organisms. However, this approach ... -
A fruit in the hand or two in the bush? Divergent risk preferences in chimpanzees and bonobos.
(Biol Lett, 2008-06-23)Human and non-human animals tend to avoid risky prospects. If such patterns of economic choice are adaptive, risk preferences should reflect the typical decision-making environments faced by organisms. However, this approach ... -
A Functional Polymorphism (rs2494752) in the AKT1 Promoter Region and Gastric Adenocarcinoma Risk in an Eastern Chinese Population.
(Scientific reports, 2016-01-28)AKT is an important signal transduction protein that plays a crucial role in cancer development. Therefore, we evaluated associations between single nucleotide polymorphisms (SNPs) in the AKT promoter region and gastric ... -
A functional polymorphism in the 5HTR2C gene associated with stress responses also predicts incident cardiovascular events.
(PLoS One, 2013)Previously we have shown that a functional nonsynonymous single nucleotide polymorphism (rs6318) of the 5HTR2C gene located on the X-chromosome is associated with hypothalamic-pituitary-adrenal axis response to a stress ... -
A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk of recurrence in patients with oropharyngeal cancer.
(Oncotarget, 2016-06)IL-1a, an important regulator of immune and inflammation responses, has been implicated in cancer development and prognosis. An insertion (Ins)/deletion (Del) polymorphism (IL-1a rs3783553) in the 3' UTR of IL-1a may disrupt ... -
A genetic variant in the APE1/Ref-1 gene promoter -141T/G may modulate risk of glioblastoma in a Chinese Han population.
(BMC cancer, 2011-01)BACKGROUND: The human apurinic/apyrimidinic endonuclease 1/Redox effector factor-1 (APE1/Ref-1) is implicated in tumor development and progression. Recently, the APE1/Ref-1 promoter -141T/G variant (rs1760944) has been reported ... -
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
(PLoS Genet, 2010-02-19)To investigate the underlying mechanisms of T2D pathogenesis, we looked for diabetes susceptibility genes that increase the risk of type 2 diabetes (T2D) in a Han Chinese population. A two-stage genome-wide association (GWA) ...
