Now showing items 1-11 of 11

    • 29 mammalian genomes reveal novel exaptations of mobile elements for likely regulatory functions in the human genome. 

      Lowe, Craig; Haussler, David (PloS one, 2012-01)
      Recent research supports the view that changes in gene regulation, as opposed to changes in the genes themselves, play a significant role in morphological evolution. Gene regulation is largely dependent on transcription ...
    • A high-resolution map of human evolutionary constraint using 29 mammals. 

      Lowe, Craig; Lindblad-Toh, Kerstin; Garber, Manuel; Zuk, Or; Lin, Michael F; Parker, Brian J; Washietl, Stefan; ... (86 authors) (Nature, 2011-10-12)
      The comparison of related genomes has emerged as a powerful lens for genome interpretation. Here we report the sequencing and comparative analysis of 29 eutherian genomes. We confirm that at least 5.5% of the human genome ...
    • Behavioural and physiological limits to vision in mammals. 

      Field, Greg; Sampath, Alapakkam P (Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2017-04)
      Human vision is exquisitely sensitive-a dark-adapted observer is capable of reliably detecting the absorption of a few quanta of light. Such sensitivity requires that the sensory receptors of the retina, rod photoreceptors, ...
    • Dynamic evolution of the alpha (α) and beta (β) keratins has accompanied integument diversification and the adaptation of birds into novel lifestyles. 

      Bao, W; Gilbert, M Thomas P; Greenwold, MJ; Hu, H; Jarvis, Erich David; Li, C; Sawyer, RH; ... (8 authors) (BMC Evol Biol, 2014-12-12)
      BACKGROUND: Vertebrate skin appendages are constructed of keratins produced by multigene families. Alpha (α) keratins are found in all vertebrates, while beta (β) keratins are found exclusively in reptiles and birds. We ...
    • Endangered species hold clues to human evolution. 

      Lowe, Craig; Bejerano, Gill; Salama, Sofie R; Haussler, David (The Journal of heredity, 2010-07)
      We report that 18 conserved, and by extension functional, elements in the human genome are the result of retroposon insertions that are evolving under purifying selection in mammals. We show evidence that 1 of the 18 elements ...
    • Environmental fate and effects of Bacillus thuringiensis (Bt) proteins from transgenic crops: a review. 

      Clark, BW; Phillips, TA; Coats, JR (Journal of agricultural and food chemistry, 2005-06)
      This paper reviews the scientific literature addressing the environmental fate and nontarget effects of the Cry protein toxins from Bacillus thuringiensis (Bt), specifically resulting from their expression in transgenic ...
    • Evidence for a single loss of mineralized teeth in the common avian ancestor. 

      Gilbert, M Thomas P; Jarvis, Erich David; Meredith, RW; Springer, MS; Zhang, G (Science, 2014-12-12)
      Edentulism, the absence of teeth, has evolved convergently among vertebrates, including birds, turtles, and several lineages of mammals. Instead of teeth, modern birds (Neornithes) use a horny beak (rhamphotheca) and a muscular ...
    • Evolution of networks and sequences in eukaryotic cell cycle control. 

      Cross, FR; Buchler, NE; Skotheim, JM (Philos Trans R Soc Lond B Biol Sci, 2011-12-27)
      The molecular networks regulating the G1-S transition in budding yeast and mammals are strikingly similar in network structure. However, many of the individual proteins performing similar network roles appear to have unrelated ...
    • Mammal Diversity, Persistence, and Conservation in India 

      Karanth, Krithi K (2008-12-03)
      Biodiversity conservation issues are complex and contentious. In this dissertation, I focus on Indian mammal conservation science, management, as well as policy issues that shape these factors. I am particularly interested ...
    • Overview of FEED, the feeding experiments end-user database. 

      Gapeyev, V; German, RZ; Lapp, Hilmar; Liu, X; Vinyard, CJ; Wall, CE; Williams, SH (Integr Comp Biol, 2011-08)
      The Feeding Experiments End-user Database (FEED) is a research tool developed by the Mammalian Feeding Working Group at the National Evolutionary Synthesis Center that permits synthetic, evolutionary analyses of the physiology ...
    • The genome of the green anole lizard and a comparative analysis with birds and mammals. 

      Lowe, Craig; Alföldi, Jessica; Di Palma, Federica; Grabherr, Manfred; Williams, Christina; Kong, Lesheng; Mauceli, Evan; ... (50 authors) (Nature, 2011-08-31)
      The evolution of the amniotic egg was one of the great evolutionary innovations in the history of life, freeing vertebrates from an obligatory connection to water and thus permitting the conquest of terrestrial environments. ...