Browsing by Subject "Mass spectrometry"
Now showing items 1-7 of 7
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Biomarkers and proteomic analysis of osteoarthritis.
(Matrix Biol, 2014-10)Our friend and colleague, Dr. Dick Heinegård, contributed greatly to the understanding of joint tissue biochemistry, the discovery and validation of arthritis-related biomarkers and the establishment of methodology for proteomic ... -
Computational Mass Spectrometry
(2015)Conventional mass spectrometry sensing has isomorphic nature, which means measure the input mass spectrum abundance function by a resemble of delta function to avoid ambiguity. However, the delta function nature of traditional ... -
Development and Application of Large-Scale Protein Folding Stability Analysis in Drug Target Identification and Disease Biomarker Discovery
(2020)In the past decade, several mass spectrometry-based proteomic techniques have been developed for the large-scale analysis of protein folding stabilities. The main focus of this dissertation is to develop and apply these ... -
Development and Application of a quantitative Mass spectrometry based Platform for Thermodynamic Analysis of Protein interaction Networks
(2013)The identification and quantification of protein-protein interactions in large scale is critical to understanding biological processes at a systems level. Current approaches for the analysis of protein -protein interactions ... -
Improving Mass Spectrometry-Based Metabolite Identification and Quantification and Application to Cardiovascular Disease
(2017)High-throughput molecular profiling is being increasingly applied to identify novel biomarkers and mechanisms of health and disease. One such application is the use of mass spectrometry-based metabolomic profiling ... -
Investigation Into Molecular Mechanisms of Substrate Recognition for Chlamydial Protease-Like Activity Factor (CPAF)
(2015)The obligate intracellular pathogen, Chlamydia trachomatis, is becoming an ever greater public health threat worldwide. Despite aggressive public health awareness campaigns and treatment with antibiotics, chlamydial infections ... -
The cellular lipids of Romboutsia.
(Biochim Biophys Acta, 2016-09)We have examined the lipids of three isolates, Romboutsia lituseburensis, Romboutsia ilealis, and Romboutsia sp. strain FRIFI, of the newly described genus Romboutsia by two-dimensional thin-layer chromatography (2D-TLC) ...
