Browsing by Subject "Mediator Complex Subunit 1"

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    • Molecular determinants for enzalutamide-induced transcription in prostate cancer. 

      Yuan, Fuwen; Hankey, William; Wu, Dayong; Wang, Hongyan; Somarelli, Jason; Armstrong, Andrew J; Huang, Jiaoti; ... (9 authors) (Nucleic acids research, 2019-11)
      Enzalutamide, a second-generation androgen receptor (AR) antagonist, has demonstrated clinical benefit in men with prostate cancer. However, it only provides a temporary response and modest increase in survival, indicating ...