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Browsing by Subject "Meiosis"
Now showing items 1-8 of 8
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Across the meiotic divide - CSF activity in the post-Emi2/XErp1 era.
(J Cell Sci, 2008-11-01)Vertebrate eggs are arrested at the metaphase stage of meiosis II. Only upon fertilization will the metaphase-II-arrested eggs exit meiosis II and enter interphase. In 1971, Masui and Markert injected egg extracts into a ... -
Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A.
(Proc Natl Acad Sci U S A, 2007-10-16)Before fertilization, vertebrate eggs are arrested in meiosis II by cytostatic factor (CSF), which holds the anaphase-promoting complex (APC) in an inactive state. It was recently reported that Mos, an integral component ... -
Functional epialleles at an endogenous human centromere.
(Proc Natl Acad Sci U S A, 2012-08-21)Human centromeres are defined by megabases of homogenous alpha-satellite DNA arrays that are packaged into specialized chromatin marked by the centromeric histone variant, centromeric protein A (CENP-A). Although most human ... -
Gene expression in oogenesis and implications for transgenerational effects of environmental toxicants.
(Biology of reproduction, 2011-01) -
Genomic and functional variation of human centromeres.
(Experimental cell research, 2020-04)Centromeres are central to chromosome segregation and genome stability, and thus their molecular foundations are important for understanding their function and the ways in which they go awry. Human centromeres typically ... -
Kinesins at a glance.
(J Cell Sci, 2010-10-15) -
The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe.
(PLoS One, 2010-12-20)A strand-specific transcriptome sequencing strategy, directional ligation sequencing or DeLi-seq, was employed to profile antisense transcriptome of Schizosaccharomyces pombe. Under both normal and heat shock conditions, ... -
Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast.
(Genetics, 2012-02)Many essential aspects of genome function, including gene expression and chromosome segregation, are mediated throughout development and differentiation by changes in the chromatin state. Along with genomic signals encoded ...