Browsing by Subject "Models, Theoretical"
Now showing items 1-20 of 57
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A community approach to mortality prediction in sepsis via gene expression analysis.
(Nature communications, 2018-02)Improved risk stratification and prognosis prediction in sepsis is a critical unmet need. Clinical severity scores and available assays such as blood lactate reflect global illness severity with suboptimal performance, and ... -
A mathematical model for persistent post-CSD vasoconstriction.
(PLoS computational biology, 2020-07-15)Cortical spreading depression (CSD) is the propagation of a relatively slow wave in cortical brain tissue that is linked to a number of pathological conditions such as stroke and migraine. Most of the existing literature ... -
A novel framework for analyzing conservation impacts: evaluation, theory, and marine protected areas.
(Ann N Y Acad Sci, 2017-07)Environmental conservation initiatives, including marine protected areas (MPAs), have proliferated in recent decades. Designed to conserve marine biodiversity, many MPAs also seek to foster sustainable development. As is ... -
A population model of folate-mediated one-carbon metabolism.
(Nutrients, 2013-07-05)BACKGROUND: Previous mathematical models for hepatic and tissue one-carbon metabolism have been combined and extended to include a blood plasma compartment. We use this model to study how the concentrations of metabolites ... -
A Systematic Review of Conceptual Frameworks of Medical Complexity and New Model Development.
(J Gen Intern Med, 2016-03)BACKGROUND: Patient complexity is often operationalized by counting multiple chronic conditions (MCC) without considering contextual factors that can affect patient risk for adverse outcomes. OBJECTIVE: Our objective was ... -
An analysis from the Quality Outcomes Database, Part 2. Predictive model for return to work after elective surgery for lumbar degenerative disease.
(Journal of neurosurgery. Spine, 2017-10)OBJECTIVE Current costs associated with spine care are unsustainable. Productivity loss and time away from work for patients who were once gainfully employed contributes greatly to the financial burden experienced by individuals ... -
Application description and policy model in collaborative environment for sharing of information on epidemiological and clinical research data sets.
(PLoS One, 2010-02-19)BACKGROUND: Sharing of epidemiological and clinical data sets among researchers is poor at best, in detriment of science and community at large. The purpose of this paper is therefore to (1) describe a novel Web application ... -
Application of Edwards' statistical mechanics to high-dimensional jammed sphere packings.
(Phys Rev E Stat Nonlin Soft Matter Phys, 2010-11)The isostatic jamming limit of frictionless spherical particles from Edwards' statistical mechanics [Song et al., Nature (London) 453, 629 (2008)] is generalized to arbitrary dimension d using a liquid-state description. ... -
Can prospect theory explain risk-seeking behavior by terminally ill patients?
(Med Decis Making, 2005-11)Patients with life-threatening conditions sometimes appear to make risky treatment decisions as their condition declines, contradicting the risk-averse behavior predicted by expected utility theory. Prospect theory accommodates ... -
Characterizing the Switching Thresholds of Magnetophoretic Transistors.
(Adv Mater, 2015-10-28)The switching thresholds of magnetophoretic transistors for sorting cells in microfluidic environments are characterized. The transistor operating conditions require short 20-30 mA pulses of electrical current. By demonstrating ... -
Climate adaptation and policy-induced inflation of coastal property value.
(PLoS One, 2015)Human population density in the coastal zone and potential impacts of climate change underscore a growing conflict between coastal development and an encroaching shoreline. Rising sea-levels and increased storminess threaten ... -
Comparing habitat suitability and connectivity modeling methods for conserving pronghorn migrations.
(PloS one, 2012-01)Terrestrial long-distance migrations are declining globally: in North America, nearly 75% have been lost. Yet there has been limited research comparing habitat suitability and connectivity models to identify migration corridors ... -
Comparing the model-simulated global warming signal to observations using empirical estimates of unforced noise.
(Sci Rep, 2015-04-21)The comparison of observed global mean surface air temperature (GMT) change to the mean change simulated by climate models has received much public and scientific attention. For a given global warming signal produced by ... -
Complex k band diagrams of 3D metamaterial/photonic crystals.
(Opt Express, 2011-09-26)A finite element method (FEM) for solving a complex valued k(ω) vs. ω dispersion curve of a 3D metamaterial/photonic crystal system is presented. This 3D method is a generalization of a previously reported 2D eigenvalue ... -
Cost of capital to the hospital sector.
(J Health Econ, 1988-03)This paper provides estimates of the cost of equity and debt capital to for-profit and non-profit hospitals in the U.S. for the years 1972-83. The cost of equity is estimated using, alternatively, the Capital Asset Pricing ... -
CPT to RVU conversion improves model performance in the prediction of surgical case length.
(Scientific reports, 2021-07-08)Methods used to predict surgical case time often rely upon the current procedural terminology (CPT) code as a nominal variable to train machine-learned models, however this limits the ability of the model to incorporate ... -
Cultural conformity generates extremely stable traditions in bird song.
(Nature communications, 2018-06)Cultural traditions have been observed in a wide variety of animal species. It remains unclear, however, what is required for social learning to give rise to stable traditions: what level of precision and what learning strategies ... -
Cumulative early life adversity predicts longevity in wild baboons.
(Nat Commun, 2016-04-19)In humans and other animals, harsh circumstances in early life predict morbidity and mortality in adulthood. Multiple adverse conditions are thought to be especially toxic, but this hypothesis has rarely been tested in a ... -
Dimensional study of the dynamical arrest in a random Lorentz gas.
(Phys Rev E Stat Nonlin Soft Matter Phys, 2015-04)The random Lorentz gas (RLG) is a minimal model for transport in heterogeneous media. Upon increasing the obstacle density, it exhibits a growing subdiffusive transport regime and then a dynamical arrest. Here, we study ... -
Discharge competence and pattern formation in peatlands: a meta-ecosystem model of the Everglades ridge-slough landscape.
(PLoS One, 2013)Regular landscape patterning arises from spatially-dependent feedbacks, and can undergo catastrophic loss in response to changing landscape drivers. The central Everglades (Florida, USA) historically exhibited regular, linear, ...
