Browsing by Subject "Myc"
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Explore Rb/E2F Activation Dynamics to Define the Control Logic of Cell Cycle Entry in Single Cells
(2015)Control of E2F transcription factor activity, regulated by the action of the retinoblastoma tumor suppressor, is critical for determining cell cycle entry and cell proliferation. However, an understanding of the precise ... -
Integrative Analysis of the Myc and E2F pathway Reveal the Roles for microRNAs in Cell Fate Control
(2011)Cancer is a disease state that arises as a result of multiple alterations in signaling pathways that are critical for making key cell fate decisions in normal cells. Understanding how these pathways operate under normal ...