Browsing by Subject "Neuralgia"

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Lack of evidence for ectopic sprouting of genetically labeled Aβ touch afferents in inflammatory and neuropathic trigeminal pain.

Chen, Y; Liedtke, Wolfgang Bernhard; Wang, Fan; Zhang, Y (Mol Pain, 2015-04-10)

BACKGROUND: Mechanical and in particular tactile allodynia is a hallmark of chronic pain in which innocuous touch becomes painful. Previous cholera toxin B (CTB)-based neural tracing experiments and electrophysiology studies ...
Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance.

Caron, MG; Chavkin, C; Czyzyk, TA; Lefkowitz, Robert J; McLaughlin, JP; Petraschka, M; Pintar, JE; ... (10 authors) (J Neurosci, 2004-05-12)

Release of endogenous dynorphin opioids within the spinal cord after partial sciatic nerve ligation (pSNL) is known to contribute to the neuropathic pain processes. Using a phosphoselective antibody [kappa opioid receptor ...