Browsing by Subject "Neurons"
Now showing items 1-20 of 106
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16-Channel biphasic current-mode programmable charge balanced neural stimulation.
(Biomedical engineering online, 2017-08)<h4>Background</h4>Neural stimulation is an important method used to activate or inhibit action potentials of the neuronal anatomical targets found in the brain, central nerve and peripheral nerve. The neural stimulator ... -
A membrane-associated progesterone-binding protein, 25-Dx, is regulated by progesterone in brain regions involved in female reproductive behaviors.
(Proc Natl Acad Sci U S A, 2000-11-07)The ventromedial hypothalamus (VMH) plays a central role in the regulation of the female reproductive behavior lordosis, a behavior dependent upon the sequential activation of receptors for the ovarian steroid hormones estradiol ... -
A mutual information analysis of neural coding of speech by low-frequency MEG phase information.
(J Neurophysiol, 2011-08)Recent work has implicated low-frequency (<20 Hz) neuronal phase information as important for both auditory (<10 Hz) and speech [theta (∼4-8 Hz)] perception. Activity on the timescale of theta corresponds linguistically ... -
A pathway in primate brain for internal monitoring of movements.
(Science, 2002-05-24)It is essential to keep track of the movements we make, and one way to do that is to monitor correlates, or corollary discharges, of neuronal movement commands. We hypothesized that a previously identified pathway from brainstem ... -
A Refined Neuronal Population Measure of Visual Attention.
(PloS one, 2015-01)Neurophysiological studies of cognitive mechanisms such as visual attention typically ignore trial-by-trial variability and instead report mean differences averaged across many trials. Advances in electrophysiology allow ... -
A relationship between behavior, neurotrophin expression, and new neuron survival.
(Proc Natl Acad Sci U S A, 2000-07-18)The high vocal center (HVC) controls song production in songbirds and sends a projection to the robust nucleus of the archistriatum (RA) of the descending vocal pathway. HVC receives new neurons in adulthood. Most of the ... -
A screw microdrive for adjustable chronic unit recording in monkeys.
(J Neurosci Methods, 1998-06-01)A screw microdrive is described that attaches to the grid system used for recording single neurons from brains of awake behaving monkeys. Multiple screwdrives can be mounted on a grid over a single cranial opening. This ... -
A Three-Threshold Learning Rule Approaches the Maximal Capacity of Recurrent Neural Networks.
(PLoS Comput Biol, 2015-08)Understanding the theoretical foundations of how memories are encoded and retrieved in neural populations is a central challenge in neuroscience. A popular theoretical scenario for modeling memory function is the attractor ... -
Acetylcholine Modulates Cerebellar Granule Cell Spiking by Regulating the Balance of Synaptic Excitation and Inhibition.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020-04)Sensorimotor integration in the cerebellum is essential for refining motor output, and the first stage of this processing occurs in the granule cell layer. Recent evidence suggests that granule cell layer synaptic integration ... -
Activation of the ATF6 (Activating Transcription Factor 6) Signaling Pathway in Neurons Improves Outcome After Cardiac Arrest in Mice.
(Journal of the American Heart Association, 2021-06-11)Background Ischemia/reperfusion injury impairs proteostasis, and triggers adaptive cellular responses, such as the unfolded protein response (UPR), which functions to restore endoplasmic reticulum homeostasis. After cardiac ... -
Activation of the ATF6 branch of the unfolded protein response in neurons improves stroke outcome.
(Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017-03)Impaired function of the endoplasmic reticulum (ER stress) is a hallmark of many human diseases including stroke. To restore ER function in stressed cells, the unfolded protein response (UPR) is induced, which activates ... -
Advances in color science: from retina to behavior.
(The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010-11)Color has become a premier model system for understanding how information is processed by neural circuits, and for investigating the relationships among genes, neural circuits, and perception. Both the physical stimulus ... -
Analysis of the mouse transcriptome for genes involved in the function of the nervous system.
(Genome Res, 2003-06)We analyzed the mouse Representative Transcript and Protein Set for molecules involved in brain function. We found full-length cDNAs of many known brain genes and discovered new members of known brain gene families, including ... -
ApoE mimetic ameliorates motor deficit and tissue damage in rat spinal cord injury.
(Journal of neuroscience research, 2014-07)Apolipoprotein E (apoE), a plasma protein responsible for transporting lipid and cholesterol, modulates responses of the central nervous system to injury. Small peptides derived from the receptor-binding region of apoE can ... -
Astrocytes: Orchestrating synaptic plasticity?
(Neuroscience, 2016-05)Synaptic plasticity is the capacity of a preexisting connection between two neurons to change in strength as a function of neural activity. Because synaptic plasticity is the major candidate mechanism for learning and memory, ... -
Auditory signals evolve from hybrid- to eye-centered coordinates in the primate superior colliculus.
(Journal of neurophysiology, 2012-07)Visual and auditory spatial signals initially arise in different reference frames. It has been postulated that auditory signals are translated from a head-centered to an eye-centered frame of reference compatible with the ... -
Axonal growth-associated proteins.
(Annual review of neuroscience, 1989-01) -
Basal ganglia function, stuttering, sequencing, and repair in adult songbirds.
(Sci Rep, 2014-10-13)A pallial-basal-ganglia-thalamic-pallial loop in songbirds is involved in vocal motor learning. Damage to its basal ganglia part, Area X, in adult zebra finches has been noted to have no strong effects on song and its function ... -
Building an organic computing device with multiple interconnected brains.
(Scientific reports, 2015-07-09)Recently, we proposed that Brainets, i.e. networks formed by multiple animal brains, cooperating and exchanging information in real time through direct brain-to-brain interfaces, could provide the core of a new type of computing ... -
Chaos in percepts?
(Biol Cybern, 1994)Multistability in perceptual tasks has suggested that the mechanisms underlying our percepts might be modeled as nonlinear, deterministic systems that exhibit chaotic behavior. We present evidence supporting this view, obtaining ...
