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Browsing by Subject "Neuroscience"
Now showing items 1-13 of 13
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APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1.
(The Journal of clinical investigation, 2019-02-11)Carrying the ε4 allele of the APOE gene encoding apolipoprotein E (APOE4) markedly increases the risk for late-onset Alzheimer's disease (AD), in which APOE4 exacerbates the brain accumulation and subsequent deposition of ... -
Internal vs. External Attention and the Neurocognitive Processes of Subsequent Memory
(2018-04-25)The capacity to store large amounts of information is increasingly relevant in today’s data-saturated society. Two subtypes of our attentional mechanisms are known as internal and external attention, and are respectively ... -
Investigating Contemplative Christian Spirituality as Christian Formation through a Process Hermeneutic: an analysis of History, Evolution, and Neuroscience in Christian Meditation
(2020)“Investigating Contemplative Christian Spirituality as Christian Formation through a Process Hermeneutic: an analysis of History, Evolution, and Neuroscience in Christian Meditation” argues that a contemplative approach ... -
Investigating Contemplative Christian Spirituality as Christian Formation through a Process Hermeneutic: an analysis of History, Evolution, and Neuroscience in Christian Meditation
(2020)“Investigating Contemplative Christian Spirituality as Christian Formation through a Process Hermeneutic: an analysis of History, Evolution, and Neuroscience in Christian Meditation” argues that a contemplative approach ... -
Investigating the Histopathology and Co-prevalence of Age-related Macular Degeneration and Alzheimer's Disease
(2017-05-08)PURPOSE: To investigate the parallels between age-related macular degeneration (AMD) and Alzheimer’s disease (AD) by 1) characterizing the distribution of macrophages in the retina and choroid of human post-mortem eyes ... -
L'Épilepsie comme "crise" de la conscience: Perspectives narratives, philosophiques, et neuroscientifiques
(2019-04-16)“Each seizure is like a sort of hemorrhage of innervation. The center of image formation in my brain suffers a seminal leak, a hundred thousand images erupt at once, in visual fireworks. There is an atrocious clenching of ... -
Leadership for Thriving: A Framework to Lead the Business Community to Sustainable Behaviors
(2023-04-25)Climate change is a complex problem whose solution is still far from being on track. Although we have advanced a lot in terms of knowledge and awareness of the problem, we are struggling to transition to sustainable actions. ... -
Making Sense of Normative Functions and Information in Neurobiological Systems
(2012)In this thesis, I take up two important issues for understanding neurobiological systems: normative functions and information. After introducing the topic and my methodology in chapters 1 and 2, chapter 3 contains an extended ... -
Object and spatial subsystems in mental imagery : behavioral investigations
(1994)Recent evidence indicates that mental imagery comprises independent object and spatial subsystems. The experiments reported here are behavioral studies of these subsystems. Experiments 1 and 2 used the selective interference ... -
Sparcl1/Hevin drives pathological pain through spinal cord astrocyte and NMDA receptor signaling.
(JCI insight, 2022-10)Hevin/Sparcl1 is an astrocyte-secreted protein and regulates synapse formation. Here we show that astrocytic hevin signaling plays a critical role in maintaining chronic pain. Compared to wild-type mice, hevin-null mice ... -
Subjective duration as a signature of coding efficiency: Emerging links among stimulus repetition, predictive coding, and cortical GABA levels
(Timing & Time Perception Reviews, 2014-12-01)Immediate repetition of a stimulus reduces its apparent duration relative to a novel item. Recent work indicates that this may reflect suppressed cortical responses to repeated stimuli, arising from neural adaptation and/or ... -
To Pernambuco with Love for Wind Symphony; String Quartet No. 1; Maco Light for Bass Clarinet and Prerecorded Electronics; and Educating for Composition Creativity
(2019)The structure of this dissertation comprises an introduction and four chapters, which contain three original musical compositions and one article. The first composition is a piece for wind symphony, the second one works ... -
Traditional and Computational Engineering of Genetically Encoded Indicators and Actuators for Neuroscience Applications
(2023)The brain supports numerous complex processes ranging from signal processing and motor control to learning and memory. These processes rely on signal transduction between interconnected networks of neurons that form neural ...
