Browsing by Subject "PET"
Now showing items 1-17 of 17
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Assessing Dose Components to PET Technologists; Exploration of Novel Approach to PET Facility Shielding Design
(2012)Purpose: (1) To verify the accuracy and linearity of the ThermoScientific Radeye G Personal Rate Meter with respect to exposure rate across the full dynamic range of the instrument. (2) Use a combination of empirical data ... -
Characterization of Gynecological Tumors using Texture Analysis in the Context of an 18F-FDG Adaptive PET Protocol
(2015)In radiation oncology, 18F-FDG Positron Emission Tomography (PET) is used for determining metabolic activity of cancers as well as delineating gross tumor volumes (GTV) for treatment planning. More recently, PET is being ... -
Data-Driven Motion Detection and Characterization in PET Brain Scans Using List Mode
(2016)Head motion during a Positron Emission Tomography (PET) brain scan can considerably degrade image quality. External motion-tracking devices have proven successful in minimizing this effect, but the associated time, maintenance, ... -
Effect of 18F-FDG PET image discretization on radiomic features of patients undergoing definitive radiotherapy for oropharyngeal cancer
(2022)Purpose: To characterize the effect of different discretization techniques (methods and values) on radiomic features extracted from positron emission tomography (PET) images of patients undergoing definitive radiotherapy ... -
Evaluation of Centrally Located Sources in Coincidence Timing Calibration for Time-of-Flight PET
(2012)Coincidence Timing Calibration (CTC) is an essential part of ensuring proper PET scanner function. The purpose of CTC is to account for timing differences in detector modules. The importance and precision in which this ... -
Fluorine-18 Labeling of the MDM2 Inhibitor RG7388 for PET Imaging: Chemistry and Preliminary Evaluation.
(Molecular pharmaceutics, 2021-09-15)RG7388 (Idasanutlin) is a potent inhibitor of oncoprotein murine double minute 2 (MDM2). Herein we investigated the feasibility of developing 18F-labeled RG7388 as a radiotracer for imaging MDM2 expression in tumors with ... -
Incremental value of PET and MRI in the evaluation of cardiovascular abnormalities.
(Insights Imaging, 2016-08)The cardiovascular system is affected by a wide range of pathological processes, including neoplastic, inflammatory, ischemic, and congenital aetiology. Magnetic resonance imaging (MRI) and positron emission tomography (PET) ... -
Low-level whole-brain radiation enhances theranostic potential of single-domain antibody fragments for human epidermal growth factor receptor type 2 (HER2)-positive brain metastases.
(Neuro-oncology advances, 2022-01)<h4>Background</h4>Single-domain antibody fragments (aka VHH, ~ 13 kDa) are promising delivery systems for brain tumor theranostics; however, achieving efficient delivery of VHH to intracranial lesions remains challenging ... -
Partial & Full CT-guided SPECT/PET Imaging of Pelvis Bone Lesions for Partial Volume Correction: A Simulation Study
(2021)AbstractIntroduction: SPECT and PET are long established methods for functional imaging of bone lesions, including lesions in bone marrow and bone metastasis. These imaging modalities are however limited by poor spatial ... -
PET Image Quality in the Vicinity of the Bladder with Fluorine-18 and Gallium-68
(2018)Gallium-68 labeled compounds have shown an important role in PET imaging of detecting neuroendocrine tumors and prostate tumors. As the prostate exists near the bladder, image quality of prostate tumors can be challenged ... -
PET Lesion Quantitation Noise Estimates from Sub-Scan Data
(2016)The use of Positron Emission Tomography (PET) has been suggested as a tool for quantitative biological measurement to determine outcomes of therapy, diagnosis, and novel drugs, through measures of tumor change from repeated ... -
Semi-Quantitative Metrics in Positron Emission Tomography
(2010)The Standardized Uptake Value (SUV) is a method for semiquantitative evaluation of radiotracer accumulation on PET scans. Changes in SUV can be used to determine treatment response. However, SUV measurements are influenced ... -
Standardization of Small Lesion Contrast in PET Imaging
(2014)Quantitative measurements in PET imaging have recently become more widespread as a way to diagnose and stage many types of malignant cancer. Currently patients need to have follow-up scans performed on the same PET system ... -
SUV Analysis of F-18 FDG PET Imaging in the Vicinity of the Bladder
(2012)Positron Emission Tomography with 18F-FDG can be used as a predictor for post-therapeutic tumor response in rectal and gynecologic cancers. An issue with assessing lesions in the vicinity of the bladder is the radioactivity ... -
The Effects of Attenuation and Scatter Correction on Positron Emission Tomography Quantitation
(2015)X-ray computed tomography (CT) forms the basis for attenuation corrected positron emission tomography (PET) using combined PET/CT scanners. With concerns of high radiation exposure to patients through widespread use of CT, ... -
The Effects of PET Reconstruction Parameters on Radiotherapy Response Assessment and an Investigation of SUV-peak Sampling Parameters
(2013)<bold>Purpose:</bold> Our primary goal was to examine the effect of PET image reconstruction parameters on baseline and early-treatment FDG-PET/CT quantitative imaging. Early-treatment changes in tumor metabolism in primary ... -
Time-of-Flight PET Compared to Increased Scan Time in Low-Contrast Regions
(2011)Positron Emission Tomography is a coincidence-detection-based nuclear imaging modality that has increased in clinical prevalence over the last two decades. Measures have recently been taken to improve the practice, specifically ...
