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Browsing by Subject "Pain"
Now showing items 1-20 of 48
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A Controlled Breathing Intervention for Women Undergoing MRI-Guided Breast Biopsy: A Randomized Controlled Trial
(2020)Controlled breathing techniques are widely used to help people manage pain, and there is growing interest in using these approaches during painful outpatient medical procedures. The outpatient MRI-guided breast biopsy is ... -
A value proposition for early physical therapist management of neck pain: a retrospective cohort analysis.
(BMC Health Serv Res, 2016-07-12)BACKGROUND: Neck pain is one of the most common reasons for entry into the healthcare system. Recent increases in healthcare utilization and medical costs have not correlated with improvements in health. Therefore there ... -
Acetabular Paralabral Cyst: An Unusual Cause of Lower Extremity Pain and Paresthesia.
(J Orthop Sports Phys Ther, 2016-01) -
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans, many of whom continue to experience persistent pain symptoms despite multiple pharmacological interventions. Preclinical data suggest ... -
Amitifadine, a triple reuptake inhibitor, reduces self-administration of the opiate remifentanil in rats.
(Psychopharmacology, 2020-06)<h4>Rationale</h4>A variety of neural systems are involved in drug addiction, and some of these systems are shared across different addictive drugs. We have found several different types of drug treatments that successfully ... -
Assessment of symptomatic rod fracture after posterior instrumented fusion for adult spinal deformity.
(Neurosurgery, 2012-10)<h4>Background</h4>Improved understanding of rod fracture (RF) in adult spinal deformity could be valuable for implant design, surgical planning, and patient counseling.<h4>Objective</h4>To evaluate symptomatic RF after ... -
Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study.
(Arthritis research & therapy, 2018-04-18)BACKGROUND:Osteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and ... -
Can unsupervised cluster analysis identify patterns of complex adult spinal deformity with distinct perioperative outcomes?
(Journal of neurosurgery. Spine, 2023-05)<h4>Objective</h4>The objective of this study was to use an unsupervised cluster approach to identify patterns of operative adult spinal deformity (ASD) and compare the perioperative outcomes of these groups.<h4>Methods</h4>A ... -
Changes in radiographic and clinical outcomes with primary treatment adult spinal deformity surgeries from two years to three- to five-years follow-up.
(Spine, 2010-09)<h4>Study design</h4>Retrospective analysis of data entered prospectively into a multicenter database-clinical and radiographic outcomes assessment.<h4>Objective</h4>Our hypothesis is that between the 2-year and the 3- to ... -
Chronic Lyme disease: the controversies and the science.
(Expert Rev Anti Infect Ther, 2011-07)The diagnosis of chronic Lyme disease has been embroiled in controversy for many years. This is exacerbated by the lack of a clinical or microbiologic definition, and the commonality of chronic symptoms in the general population. ... -
Co-occurring Fatigue and Lymphatic Pain Incrementally Aggravate Their Negative Effects on Activities of Daily Living, Emotional Distress, and Overall Health of Breast Cancer Patients.
(Integrative cancer therapies, 2022-01)<h4>Background</h4>Fatigue and lymphatic pain are the most common and debilitating long-term adverse effects of breast cancer treatment. Fatigue and pain independently have negative effects on quality of life, physical functions, ... -
Comparable satisfaction and clinical outcomes after surgery for adolescent idiopathic scoliosis in the adult (AISA) between the US and Japan.
(Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2023-01)<h4>Background</h4>The impact of ethnicity on the surgery outcomes of adolescent idiopathic scoliosis in the adult (AISA) is poorly understood. This study aimed to compare the surgery outcomes for AISA between the United ... -
Comprehensive study of back and leg pain improvements after adult spinal deformity surgery: analysis of 421 patients with 2-year follow-up and of the impact of the surgery on treatment satisfaction.
(Journal of neurosurgery. Spine, 2015-05)OBJECT Back and leg pain are the primary outcomes of adult spinal deformity (ASD) and predict patients' seeking of surgical management. The authors sought to characterize changes in back and leg pain after operative ... -
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
(Arthritis Res Ther, 2010)INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ... -
Establishment of an Individualized Distal Junctional Kyphosis Risk Index following the Surgical Treatment of Adult Cervical Deformities.
(Spine, 2023-01)<h4>Study design</h4>A retrospective review of a multicenter comprehensive cervical deformity (CD) database.<h4>Objective</h4>To develop a novel risk index specific to each patient to aid in patient counseling and surgical ... -
Examination of Adult Spinal Deformity Patients Undergoing Surgery with Implanted Spinal Cord Stimulators and Intrathecal Pumps.
(Spine, 2022-02)<h4>Study design</h4>Retrospective cohort study of a prospectively collected multi-center database of adult spinal deformity (ASD) patients.<h4>Objective</h4>We hypothesized that patients undergoing ASD surgery with and ... -
Functional outcome measures in a surgical model of hip osteoarthritis in dogs.
(J Exp Orthop, 2016-12)BACKGROUND: The hip is one of the most common sites of osteoarthritis in the body, second only to the knee in prevalence. However, current animal models of hip osteoarthritis have not been assessed using many of the functional ... -
Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.
(J Orthop Res, 2011-05)Interleukin-1 beta (IL1β) is a proinflammatory cytokine that mediates arthritic pathologies. Our objectives were to evaluate pain and limb dysfunction resulting from IL1β over-expression in the rat knee and to investigate ... -
General Anesthetics Activate a Central Pain-Suppression Circuit in the Amygdala
(2020)General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA suppresses pain in part by activating supraspinal ... -
Impact of obesity on complications and outcomes: a comparison of fusion and nonfusion lumbar spine surgery.
(Journal of neurosurgery. Spine, 2017-02)OBJECTIVE Prior studies have shown obesity to be associated with higher complication rates but equivalent clinical outcomes following lumbar spine surgery. These findings have been reproducible across lumbar spine surgery ...