Browsing by Subject "Pain"
Now showing items 1-20 of 26
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A Controlled Breathing Intervention for Women Undergoing MRI-Guided Breast Biopsy: A Randomized Controlled Trial
(2020)Controlled breathing techniques are widely used to help people manage pain, and there is growing interest in using these approaches during painful outpatient medical procedures. The outpatient MRI-guided breast biopsy is ... -
A value proposition for early physical therapist management of neck pain: a retrospective cohort analysis.
(BMC Health Serv Res, 2016-07-12)BACKGROUND: Neck pain is one of the most common reasons for entry into the healthcare system. Recent increases in healthcare utilization and medical costs have not correlated with improvements in health. Therefore there ... -
Acetabular Paralabral Cyst: An Unusual Cause of Lower Extremity Pain and Paresthesia.
(J Orthop Sports Phys Ther, 2016-01) -
Allopregnanolone Levels Are Inversely Associated with Self-Reported Pain Symptoms in U.S. Iraq and Afghanistan-Era Veterans: Implications for Biomarkers and Therapeutics.
(Pain Med, 2016-01)BACKGROUND AND OBJECTIVES: Pain symptoms are common among Iraq/Afghanistan-era veterans, many of whom continue to experience persistent pain symptoms despite multiple pharmacological interventions. Preclinical data suggest ... -
Association between general joint hypermobility and knee, hip, and lumbar spine osteoarthritis by race: a cross-sectional study.
(Arthritis research & therapy, 2018-04-18)BACKGROUND:Osteoarthritis (OA) prevalence differs by race. General joint hypermobility (GJH) may be associated with OA, but differences by race are not known. This community-based study examined the frequency of GJH and ... -
Chronic Lyme disease: the controversies and the science.
(Expert Rev Anti Infect Ther, 2011-07)The diagnosis of chronic Lyme disease has been embroiled in controversy for many years. This is exacerbated by the lack of a clinical or microbiologic definition, and the commonality of chronic symptoms in the general population. ... -
Diet-induced obesity differentially regulates behavioral, biomechanical, and molecular risk factors for osteoarthritis in mice.
(Arthritis Res Ther, 2010)INTRODUCTION: Obesity is a major risk factor for the development of osteoarthritis in both weight-bearing and nonweight-bearing joints. The mechanisms by which obesity influences the structural or symptomatic features of ... -
Functional outcome measures in a surgical model of hip osteoarthritis in dogs.
(J Exp Orthop, 2016-12)BACKGROUND: The hip is one of the most common sites of osteoarthritis in the body, second only to the knee in prevalence. However, current animal models of hip osteoarthritis have not been assessed using many of the functional ... -
Gait and behavior in an IL1β-mediated model of rat knee arthritis and effects of an IL1 antagonist.
(J Orthop Res, 2011-05)Interleukin-1 beta (IL1β) is a proinflammatory cytokine that mediates arthritic pathologies. Our objectives were to evaluate pain and limb dysfunction resulting from IL1β over-expression in the rat knee and to investigate ... -
General Anesthetics Activate a Central Pain-Suppression Circuit in the Amygdala
(2020)General anesthesia (GA) can produce analgesia (loss of pain) independent of inducing loss of consciousness, but the underlying mechanisms remain unclear. We hypothesized that GA suppresses pain in part by activating supraspinal ... -
Introduction of a psychologically informed educational intervention for pre-licensure physical therapists in a classroom setting.
(BMC medical education, 2020-10-23)BACKGROUND:There is an increasing need for physical therapists to address psychosocial aspects of musculoskeletal pain. Psychologically informed practice is one way to deliver this type of care through the integration of ... -
Non-prescribed use of pain relievers among adolescents in the United States.
(Drug and alcohol dependence, 2008-04)We examined gender-specific prevalences, patterns, and correlates of non-prescribed use of pain relievers - mainly opioids - in a representative sample of American adolescents (N=18,678).Data were drawn from the public use ... -
Nonprescription use of pain relievers by middle-aged and elderly community-living adults: National Survey on Drug Use and Health.
(Journal of the American Geriatrics Society, 2009-07)To estimate the frequency, distribution, and correlates of nonprescription use of pain relievers by middle-aged and elderly persons in the United States.Cross-sectional data analysis of a national community survey.The 2005 ... -
Pharmacological Inhibition of TAK1 as a Therapeutic Target to Reduce Inflammation and Pain
(2020)Chronic pain is a prevalent health concern, affecting up to 100 million people in the US alone, yet treatment options remain limited. The origins of pain have been tightly linked to inflammation and in specific tumor necrosis ... -
Pramipexole Augmentation of Buprenorphine Improves Pain and Depression in Opioid Use Disorder: A Case Report.
(The primary care companion for CNS disorders, 2020-10-15) -
Preemptive intrathecal administration of endomorphins relieves inflammatory pain in male mice via inhibition of p38 MAPK signaling and regulation of inflammatory cytokines.
(Journal of neuroinflammation, 2018-11-15)BACKGROUND:Preemptive administration of analgesic drugs reduces perceived pain and prolongs duration of antinociceptive action. Whereas several lines of evidence suggest that endomorphins, the endogenous mu-opioid agonists, ... -
Relationship of intersession variation in negative pain-related affect and responses to thermally-evoked pain.
(J Pain, 2010-02)UNLABELLED: The purpose of this study was to determine whether session-specific measures of negative pain-related affect would account for longitudinal variability in the ratings of the evoked thermal pain. Pain-free subjects ... -
Reported lifetime aberrant drug-taking behaviors are predictive of current substance use and mental health problems in primary care patients.
(Pain Med, 2008-11)BACKGROUND: The aim of this report is to determine the frequency of aberrant drug behaviors and their relationship to substance abuse disorders in a large primary sample of patients receiving opioids for chronic pain. METHODS: ... -
Reporting and utilization of Patient-Reported Outcomes Measurement Information System® (PROMIS®) measures in orthopedic research and practice: a systematic review.
(Journal of orthopaedic surgery and research, 2020-11-23)BACKGROUND:The Patient-Reported Outcomes Measurement Information SystemⓇ (PROMISⓇ) is a dynamic system of psychometrically sound patient-reported outcome (PRO) measures. There has been a recent increase in the use of PROMIS ... -
Resident Challenges with Functional Limitations and Pain in Chinese Residential Care Facilities
(2017)Problem: The demand for residential care facilities is high and still increasing in China. However, the quality of care in these facilities is concerning due to lack of quality control and regulations and insufficient funding. ...
