Browsing by Subject "Parasitology"
Now showing items 1-13 of 13
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Adapting Novel Molecular Diagnostic Methods for the Detection of Plasmodium knowlesi in Sarawak, Malaysia
(2020)Background: Recent epidemiological studies demonstrate that the prevalence of the fifth major human malaria parasite, Plasmodium knowlesi (monkey malaria), is often underestimated and misdiagnosed with standard microscopy ... -
An evolutionary genomics approach towards understanding Plasmodium vivax in central Africa
(2022)Increased attention has recently been placed on understanding the natural variation of the malaria parasite Plasmodium vivax across the globe, as in 2020 alone, P. vivax caused an estimated 4.5 million malaria cases and ... -
Comparing Properties of Oscillating Gene Networks in Diverged Species
(2022)Multiple biological processes occur in a time-dependent fashion. One of the most prevalent ways of regulating rhythmic biology is by controlling the timing and dosage of gene expression. Gene regulatory networks are groups ... -
Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition.
(PLoS pathogens, 2018-06-04)The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. ... -
Exploring Tick Borne Pathogens Circulating Mongolia Through Collection of Ticks
(2017)AbstractIntroduction: Mongolia is a country known for its rich nomadic and pastoral culture, with populations of people who work in environments that are densely populated with ticks and TBP animal reservoirs. TBPs typically ... -
Factors Associated with Distribution of Leishmaniasis Disease and Vectors in Madre de Dios, Peru
(2015)While the Madre de Dios department of Peru has the nation's highest leishmaniasis incidence, limited research on the disease and its sand fly vector exists in the region. Considering the diverse and adaptive nature of sand ... -
Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development.
(Cell host & microbe, 2018-06)HIV-1 broadly neutralizing antibodies (bnAbs) require high levels of activation-induced cytidine deaminase (AID)-catalyzed somatic mutations for optimal neutralization potency. Probable mutations occur at sites of frequent ... -
Predictors, Costs, and Consequences of Larval Tapeworm Infection in Geladas (Theropithecus gelada).
(2017)Parasitism is integral to primate evolution, contributing to major life history tradeoffs with other processes critical to reproductive success and survival. I investigate how infection with the tapeworm Taenia serialis ... -
Quantification of Plasmodium falciparum Cyclophilin 19B Transcripts Via qPCR in Normal and Sickle-Trait Hemoglobin Genotypes
(2021)The sickle-cell trait hemoglobin genotype (HbAS) is known to protect against severe malaria caused by Plasmodium falciparum. However, the biological mechanisms behind this protection are not well understood. Cyclophilin ... -
Systematics, Phylogeography and Ecology of Elaphomycetaceae
(2011)This dissertation is an investigation of the systematics, phylogeography, and ecology of a globally distributed fungal family, the Elaphomycetaceae. In Chapter 1, we assess the literature on fungal phylogeography, reviewing ... -
The Effects of Parasites on Coastal Marsh Ecosystem Structure and Functioning
(2021)Recent experiments and comparative surveys in Southern US salt marshes revealed that a common larval trematode parasite, Parorchis acanthus, generated a trophic cascade that protected foundational marsh plants (Spartina ... -
The Role of Erythrocytic miRNA in the lifecycle of Plasmodium falciparum
(2012)Malaria, caused by the apicomplexan parasite Plasmodium, is a disease which affects up to 500 million people each year. Historically, malaria infection has been combated both through the control of its vector, the Anopheles ... -
Using Single-Cell Analyses to Uncover Transcriptional Heterogeneity in Plasmodium falciparum
(2018)Malaria persists as a global health problem, with 212 million cases and 429,000 deaths worldwide in 2015 alone. It is caused by the apicomplexan parasite Plasmodium, which follows a complex life cycle that consists of multiple ...
