Browsing by Subject "Phagocytosis"
Now showing items 1-8 of 8
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Association between cell-mediated demyelination and astrocyte stimulation.
(Prog Brain Res, 1992) -
Cryptococcal cell morphology affects host cell interactions and pathogenicity.
(PLoS Pathog, 2010-06-17)Cryptococcus neoformans is a common life-threatening human fungal pathogen. The size of cryptococcal cells is typically 5 to 10 microm. Cell enlargement was observed in vivo, producing cells up to 100 microm. These morphological ... -
Differential Killing of Salmonella enterica Serovar Typhi by Antibodies Targeting Vi and Lipopolysaccharide O:9 Antigen.
(PLoS One, 2016)Salmonella enterica serovar Typhi expresses a capsule of Vi polysaccharide, while most Salmonella serovars, including S. Enteritidis and S. Typhimurium, do not. Both S. Typhi and S. Enteritidis express the lipopolysaccharide ... -
EAE cerebrospinal fluid augments in vitro phagocytosis and metabolism of CNS myelin by macrophages.
(J Neurosci Res, 1992-07)Previous studies from this laboratory have shown that CNS myelin is phagocytized and metabolized by cultured rat macrophages to a much larger extent when myelin is pretreated with serum containing antibodies to ... -
Induction of anti-myelin antibodies in EAE and their possible role in demyelination.
(J Neurosci Res, 1991-12)Experimental allergic encephalomyelitis is characterized by invasion of lymphocytes and macrophages into the central nervous system resulting in inflammation, edema, and demyelination. Sera from Lewis rats from 7-95 days ... -
Mefenamic acid can attenuate depressive symptoms by suppressing microglia activation induced upon chronic stress.
(Brain research, 2020-08)BACKGROUND:Depression is the most debilitating neuropsychiatric disorder, and psychosocial stressors are major risk factors for the onset of depression. Depression is closely associated with chronic inflammation and microglia ... -
Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma.
(Proceedings of the National Academy of Sciences of the United States of America, 2019-01)Glioblastoma multiforme (GBM) is a highly aggressive malignant brain tumor with fatal outcome. Tumor-associated macrophages and microglia (TAMs) have been found to be major tumor-promoting immune cells in the tumor ... -
PEDF Deletion Induces Senescence and Defects in Phagocytosis in the RPE.
(International journal of molecular sciences, 2022-07)The retinal pigment epithelium (RPE) expresses the Serpinf1 gene to produce pigment epithelium-derived factor (PEDF), a retinoprotective protein that is downregulated with cell senescence, aging and retinal degenerations. ...
