Browsing by Subject "Pilot Projects"
Now showing items 1-20 of 52
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A pilot investigation of audiovisual processing and multisensory integration in patients with inherited retinal dystrophies.
(BMC ophthalmology, 2017-12-07)In this study, we examined audiovisual (AV) processing in normal and visually impaired individuals who exhibit partial loss of vision due to inherited retinal dystrophies (IRDs).Two groups were analyzed for this pilot study: ... -
A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma.
(PLoS One, 2012)BACKGROUND: Preclinical studies in mice have demonstrated that the prophylactic depletion of immunosuppressive regulatory T-cells (T(Regs)) through targeting the high affinity interleukin-2 (IL-2) receptor (IL-2Rα/CD25) ... -
A pilot study of orthopaedic resident self-assessment using a milestones' survey just prior to milestones implementation.
(Int J Med Educ, 2016-01-11)OBJECTIVE: To pilot test if Orthopaedic Surgery residents could self-assess their performance using newly created milestones, as defined by the Accreditation Council on Graduate Medical Education. METHODS: In June 2012, ... -
A pilot study on mindfulness based stress reduction for smokers.
(BMC complementary and alternative medicine, 2007-01-25)<h4>Background</h4>Mindfulness means paying attention in the present moment, non-judgmentally, without commentary or decision-making. We report results of a pilot study designed to test the feasibility of using Mindfulness ... -
A Pilot Study on Posterior Polyethylene Tethers to Prevent Proximal Junctional Kyphosis After Multilevel Spinal Instrumentation for Adult Spinal Deformity.
(Operative neurosurgery (Hagerstown, Md.), 2019-02)BACKGROUND:Proximal junctional kyphosis (PJK) is a common problem after multilevel spine instrumentation. OBJECTIVE:To determine if junctional tethers reduce PJK after multilevel instrumented surgery for adult spinal deformity ... -
Accessibility, availability and affordability of anti-malarials in a rural district in Kenya after implementation of a national subsidy scheme.
(Malar J, 2011-10-26)BACKGROUND: Poor access to prompt and effective treatment for malaria contributes to high mortality and severe morbidity. In Kenya, it is estimated that only 12% of children receive anti-malarials for their fever within ... -
Adjunctive albuterol enhances the response to enzyme replacement therapy in late-onset Pompe disease.
(FASEB J, 2014-05)Effective dosages for enzyme replacement therapy (ERT) in Pompe disease are much higher than for other lysosomal storage disorders, which has been attributed to low cation-independent mannose-6-phosphate receptor (CI-MPR) ... -
Anti-cholinergic load, health care utilization, and survival in people with advanced cancer: a pilot study.
(J Palliat Med, 2010-06)INTRODUCTION: Anti-cholinergic medications have been associated with increased risks of cognitive impairment, premature mortality and increased risk of hospitalisation. Anti-cholinergic load associated with medication increases ... -
Branched chain amino acid transaminase 1 (BCAT1) is overexpressed and hypomethylated in patients with non-alcoholic fatty liver disease who experience adverse clinical events: A pilot study.
(PloS one, 2018-01)<h4>Background and objectives</h4>Although the burden of non-alcoholic fatty liver disease (NAFLD) continues to increase worldwide, genetic factors predicting progression to cirrhosis and decompensation in NAFLD remain poorly ... -
Caring for Alaska Native prostate cancer survivors in primary care: a survey of Alaska Tribal Health System providers.
(Int J Circumpolar Health, 2014)BACKGROUND: Little is known about the constraints of optimizing health care for prostate cancer survivors in Alaska primary care. OBJECTIVE: To describe the experiences and attitudes of primary care providers within the ... -
Changes in Brain Resting-state Functional Connectivity Associated with Peripheral Nerve Block: A Pilot Study.
(Anesthesiology, 2016-08)BACKGROUND: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity ... -
Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254).
(Arthritis Res Ther, 2010)INTRODUCTION: Acute trauma involving the anterior cruciate ligament is believed to be a major risk factor for the development of post-traumatic osteoarthritis 10 to 20 years post-injury. In this study, to better understand ... -
Characterization of porous, dexamethasone-releasing polyurethane coatings for glucose sensors.
(Acta Biomaterialia, 2014-11)Commercially available implantable needle-type glucose sensors for diabetes management are robust analytically but can be unreliable clinically primarily due to tissue-sensor interactions. Here, we present the physical, ... -
Cherenkov emissions for studying tumor changes during radiation therapy: An exploratory study in domesticated dogs with naturally-occurring cancer.
(PloS one, 2020-01)<h4>Purpose</h4>Real-time monitoring of physiological changes of tumor tissue during radiation therapy (RT) could improve therapeutic efficacy and predict therapeutic outcomes. Cherenkov radiation is a normal byproduct of ... -
Communication practices in physician decision-making for an unstable critically ill patient with end-stage cancer.
(J Palliat Med, 2010-08)BACKGROUND: Shared decision-making has become the standard of care for most medical treatments. However, little is known about physician communication practices in the decision making for unstable critically ill patients ... -
Correlation between quantitative whole-body muscle magnetic resonance imaging and clinical muscle weakness in Pompe disease.
(Muscle & nerve, 2015-05)<h4>Introduction</h4>Previous examination of whole-body muscle involvement in Pompe disease has been limited to physical examination and/or qualitative magnetic resonance imaging (MRI). In this study we assess the feasibility ... -
Design of a Novel Low Cost Point of Care Tampon (POCkeT) Colposcope for Use in Resource Limited Settings.
(PLoS One, 2015)INTRODUCTION: Current guidelines by WHO for cervical cancer screening in low- and middle-income countries involves visual inspection with acetic acid (VIA) of the cervix, followed by treatment during the same visit or a ... -
Design of the NIDA clinical trials network validation study of tobacco, alcohol, prescription medications, and substance use/misuse (TAPS) tool.
(Contemporary clinical trials, 2016-09)Substance use and its associated use disorders are under-detected and under-treated in primary care. There is a need for a clinically useful brief screening and assessment instrument to identify primary care patients with ... -
Development of a decision aid to inform patients' and families' renal replacement therapy selection decisions.
(BMC Med Inform Decis Mak, 2012-12-01)BACKGROUND: Few educational resources have been developed to inform patients' renal replacement therapy (RRT) selection decisions. Patients progressing toward end stage renal disease (ESRD) must decide among multiple treatment ... -
Differences in quality between privately and publicly banked umbilical cord blood units: a pilot study of autologous cord blood infusion in children with acquired neurologic disorders.
(Transfusion, 2010-09)<h4>Background</h4>A pilot study was conducted to determine the safety and feasibility of intravenous administration of autologous umbilical cord blood (CB) in young children with acquired neurologic disorders. Most CB units ...
