Browsing by Subject "Platinum"

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Genetic variants of DNA repair genes predict the survival of patients with esophageal squamous cell cancer receiving platinum-based adjuvant chemotherapy.

Zhou, Fei; Zhu, Meiling; Wang, Mengyun; Qiu, Lixin; Cheng, Lei; Jia, Ming; Xiang, Jiaqing; ... (8 authors) (Journal of translational medicine, 2016-05-31)

Adjuvant chemotherapy in patients with resected esophageal squamous cell cancer (ESCC) remains controversial for its uncertain role in improving overall survival (OS). Nucleotide excision repair (NER) removes DNA-adducts ...
Platinum(II)-catalyzed intermolecular hydroamination of monosubstituted allenes with secondary alkylamines.

Toups, Kristina L; Widenhoefer, Ross A (Chem Commun (Camb), 2010-03-14)

A 1:1 mixture of (dppf)PtCl(2) and AgOTf (5 mol%) catalyzed the intermolecular hydroamination of monosubstituted allenes with secondary alkylamines at 80 degrees C to form allylic amines in good yield with selective formation ...