Browsing by Subject "Polyploid"
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Aneuploidy Tolerance in a Polyploid Organ
(2016)Endopolyploid cells (hereafter - polyploid cells), which contain whole genome duplications in an otherwise diploid organism, play vital roles in development and physiology of diverse organs such as our heart and liver. Polyploidy ... -
Regulation of Chromosome Structure During Both of the Endocycle and Mitosis is Critical for Accurate Chromosome Segregation in Polypoid Mitosis
(2017)Polyploid cells are generated through a cell cycle variant termed the endocycle. Endocycling cells undergo multiple rounds of genome duplication without an intervening mitosis. Endocycling is known to lead to alterations ...