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Browsing by Subject "Pregnancy"
Now showing items 1-20 of 126
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A novel human endogenous retroviral protein inhibits cell-cell fusion.
(Scientific reports, 2013-01)While common in viral infections and neoplasia, spontaneous cell-cell fusion, or syncytialization, is quite restricted in healthy tissues. Such fusion is essential to human placental development, where interactions between ... -
A three-dimensional culture system recapitulates placental syncytiotrophoblast development and microbial resistance.
(Science advances, 2016-03-04)In eutherians, the placenta acts as a barrier and conduit at the maternal-fetal interface. Syncytiotrophoblasts, the multinucleated cells that cover the placental villous tree surfaces of the human placenta, are directly ... -
Abnormal oxidative stress responses in fibroblasts from preeclampsia infants.
(PloS one, 2014-01)<h4>Background</h4>Signs of severe oxidative stress are evident in term placentae of infants born to mothers with preeclampsia (PE), but it is unclear whether this is a cause or consequence of the disease. Here fibroblast ... -
Acute infectious morbidity in multiple gestation.
(Infect Dis Obstet Gynecol, 2015)OBJECTIVES: Physiologic and immunologic changes in pregnancy result in increased susceptibility to infection. These shifts are more pronounced in pregnancies complicated by multiple gestation. The objective of this study ... -
Analysis of the equity of emergency medical services: a cross-sectional survey in Chongqing city.
(Int J Equity Health, 2015-12-21)BACKGROUND: Due to reform of the economic system and the even distribution of available wealth, emergency medical services (EMS) experienced greater risks in equity. This study aimed to assess the equity of EMS ... -
Antichlamydial antibodies, human fertility, and pregnancy wastage.
(Infectious diseases in obstetrics and gynecology, 2011-01)Genital infections with Chlamydia trachomatis (C. trachomatis) continue to be a worldwide epidemic. Immune response to chlamydia is important to both clearance of the disease and disease pathogenesis. Interindividual responses ... -
APOL1-G0 or APOL1-G2 Transgenic Models Develop Preeclampsia but Not Kidney Disease.
(Journal of the American Society of Nephrology : JASN, 2016-12)APOL1 risk variants are associated with kidney disease in blacks, but the mechanisms of renal injury associated with APOL1 risk variants are unknown. Because APOL1 is unique to humans and some primates, we created transgenic ... -
Are prediction models for vaginal birth after cesarean accurate?
(American journal of obstetrics and gynecology, 2019-05)BACKGROUND:The use of trial of labor after cesarean delivery calculators in the prediction of successful vaginal birth after cesarean delivery gives physicians an evidence-based tool to assist with patient counseling and ... -
Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.
(J Virol, 2015-10)UNLABELLED: Infants born to HIV-1-infected mothers in resource-limited areas where replacement feeding is unsafe and impractical are repeatedly exposed to HIV-1 throughout breastfeeding. Despite this, the majority of infants ... -
Association of maternal depression and hypothyroidism with infant gastroschisis: a population-based cohort study in Canada.
(Scientific reports, 2023-05)Gastroschisis has increased globally over recent decades, and this increase has not been explained by identified risk factors. We conducted a population-based study of infants born in Canada, 2004-2020. We used "winter" ... -
Associations between antibiotic exposure during pregnancy, birth weight and aberrant methylation at imprinted genes among offspring.
(International journal of obesity (2005), 2013-07)<h4>Objectives</h4>Low birth weight (LBW) has been associated with common adult-onset chronic diseases, including obesity, cardiovascular disease, type II diabetes and some cancers. The etiology of LBW is multi-factorial. ... -
Baby on board: olfactory cues indicate pregnancy and fetal sex in a non-human primate.
(Biol Lett, 2015-02)Olfactory cues play an integral, albeit underappreciated, role in mediating vertebrate social and reproductive behaviour. These cues fluctuate with the signaller's hormonal condition, coincident with and informative about ... -
Behavior genetics and postgenomics.
(Behav Brain Sci, 2012-10)The science of genetics is undergoing a paradigm shift. Recent discoveries, including the activity of retrotransposons, the extent of copy number variations, somatic and chromosomal mosaicism, and the nature of the epigenome ... -
Bipolar Depression: Pregnancy, Postpartum, and Lactation.
(The Psychiatric clinics of North America, 2016-03)Medication management of bipolar depression in pregnancy and lactation is best done by assessing each patient's and family's needs in detail. Keeping pregnant patients as psychiatrically stable as possible is the most important ... -
Blood lead levels among pregnant women: historical versus contemporaneous exposures.
(Int J Environ Res Public Health, 2010-04)Blood lead among pregnant women, even at modest levels, may impair offspring cognitive development. We examine whether blood lead levels (BLLs) result from current versus historic exposures, among a cohort of pregnant women. ... -
Buprenorphine compared with methadone to treat pregnant women with opioid use disorder: a systematic review and meta-analysis of safety in the mother, fetus and child.
(Addiction (Abingdon, England), 2016-12)<h4>Aims</h4>To assess the safety of buprenorphine compared with methadone to treat pregnant women with opioid use disorder.<h4>Methods</h4>We searched PubMed, Embase and the Cochrane Library from inception to February 2015 ... -
Case 1: Eye Discharge in a 10-day-old Neonate Born by Cesarean Delivery.
(Pediatrics in review, 2018-04) -
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.
(Proc Natl Acad Sci U S A, 1987-01)We have isolated and sequenced a cDNA encoding the human beta 2-adrenergic receptor. The deduced amino acid sequence (413 residues) is that of a protein containing seven clusters of hydrophobic amino acids suggestive of ... -
Chagas Disease Screening in Maternal Donors of Publicly Banked Umbilical Cord Blood, United States.
(Emerging infectious diseases, 2016-08)To assess patterns of Chagas disease, we reviewed results of screening umbilical cord blood from a US public cord blood bank during 2007-2014. Nineteen maternal donors tested positive for Trypanosoma cruzi parasites (0.04%). ... -
Characteristics of antipsychotic medication prescribing on inpatient obstetric floors.
(Archives of women's mental health, 2016-08)
