Browsing by Subject "Prosencephalon"
Now showing items 1-7 of 7
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Behaviourally driven gene expression reveals song nuclei in hummingbird brain.
(Nature, 2000-08-10)Hummingbirds have developed a wealth of intriguing features, such as backwards flight, ultraviolet vision, extremely high metabolic rates, nocturnal hibernation, high brain-to-body size ratio and a remarkable species-specific ... -
Characterization of the ubiquitin-modified proteome regulated by transient forebrain ischemia.
(Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014-03)Ubiquitylation is a posttranslational protein modification that modulates various cellular processes of key significance, including protein degradation and DNA damage repair. In animals subjected to transient cerebral ischemia, ... -
Chemogenetics-mediated acute inhibition of excitatory neuronal activity improves stroke outcome.
(Experimental neurology, 2020-04)<h4>Background and purpose</h4>Ischemic stroke significantly perturbs neuronal homeostasis leading to a cascade of pathologic events causing brain damage. In this study, we assessed acute stroke outcome after chemogenetic ... -
Neuron-specific SUMO knockdown suppresses global gene expression response and worsens functional outcome after transient forebrain ischemia in mice.
(Neuroscience, 2017-02)Small ubiquitin-like modifier (SUMO) conjugation (SUMOylation) plays key roles in neurologic function in health and disease. Neuronal SUMOylation is essential for emotionality and cognition, and this pathway is dramatically ... -
Profiling of experience-regulated proteins in the songbird auditory forebrain using quantitative proteomics.
(Eur J Neurosci, 2008-03)Auditory and perceptual processing of songs are required for a number of behaviors in songbirds such as vocal learning, territorial defense, mate selection and individual recognition. These neural processes are accompanied ... -
Rudimentary substrates for vocal learning in a suboscine.
(Nat Commun, 2013)Vocal learning has evolved in only a few groups of mammals and birds. The key neuroanatomical and behavioural links bridging vocal learners and non-learners are still unknown. Here we show that a non-vocal-learning suboscine, ... -
Small ubiquitin-like modifier 2 (SUMO2) is critical for memory processes in mice.
(FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020-11)Small ubiquitin-like modifier (SUMO1-3) conjugation (SUMOylation), a posttranslational modification, modulates almost all major cellular processes. Mounting evidence indicates that SUMOylation plays a crucial role in maintaining ...