Browsing by Subject "Prospective Studies"
Now showing items 1-20 of 115
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A blood-based biomarker panel to risk-stratify mild traumatic brain injury.
(PloS one, 2017-01)Mild traumatic brain injury (TBI) accounts for the vast majority of the nearly two million brain injuries suffered in the United States each year. Mild TBI is commonly classified as complicated (radiographic evidence of ... -
A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.
(Clin Cancer Res, 2016-01-15)PURPOSE: Cutaneous sclerosis occurs in 20% of patients with chronic graft-versus-host disease (GVHD) and can compromise mobility and quality of life. EXPERIMENTAL DESIGN: We conducted a prospective, multicenter, randomized, ... -
Acute myocardial infarction under-diagnosis and mortality in a Tanzanian emergency department: A prospective observational study.
(American heart journal, 2020-08)BACKGROUND:Growing evidence suggests that under-diagnosis of acute myocardial infarction (AMI) may be common in sub-Saharan Africa. Prospective studies of routine AMI screening among patients presenting to emergency departments ... -
AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings.
(Clin Infect Dis, 2010-11-01)AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection has not been adequately studied and poses unique therapeutic challenges in resource‐limited settings. Itraconazole poorly penetrates ... -
An analysis of emergency care delays experienced by traumatic brain injury patients presenting to a regional referral hospital in a low-income country.
(PloS one, 2020-01)<h4>Background</h4>Trauma is a leading cause of death and disability worldwide. In low- and middle-income countries (LMICs), trauma patients have a higher risk of experiencing delays to care due to limited hospital resources ... -
An evaluation of physician predictions of discharge on a general medicine service.
(J Hosp Med, 2015-12)The goal of this study was to evaluate general medicine physicians' ability to predict hospital discharge. We prospectively asked study subjects to predict whether each patient under their care would be discharged on the ... -
Are tuberculosis patients adherent to prescribed treatments in China? Results of a prospective cohort study.
(Infect Dis Poverty, 2016-05-05)BACKGROUND: Tuberculosis (TB) patients face numerous difficulties adhering to the long-term, rigorous TB treatment regimen. Findings on TB patients' treatment adherence vary across existing literature and official reports. ... -
Assessment of Macular Microvasculature in Healthy Eyes of Infants and Children Using OCT Angiography.
(Ophthalmology, 2019-12)PURPOSE:To assess macular vasculature in healthy infants and children using OCT angiography (OCTA). DESIGN:Prospective cross-sectional study. PARTICIPANTS:One hundred thirty-five normal maculae of 89 healthy infants and ... -
Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming.
(Frontiers in immunology, 2021-01)<h4>Background</h4>The immunologic pathways activated during snakebite envenoming (SBE) are poorly described, and their association with recovery is unclear. The immunologic response in SBE could inform a prognostic model ... -
Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.
(J Am Heart Assoc, 2013-03-19)BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD) patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence of depression and anxiety. We examined whether ... -
Associations between superoxide dismutase, malondialdehyde and all-cause mortality in older adults: a community-based cohort study.
(BMC geriatrics, 2019-04-15)<h4>Background</h4>Oxidative stress is an important theory of aging but population-based evidence has been lacking. This study aimed to evaluate the associations between biomarkers of oxidative stress, including plasma superoxide ... -
At-Home Versus In-Clinic INR Monitoring: A Cost-Utility Analysis from The Home INR Study (THINRS).
(Journal of general internal medicine, 2016-09)<h4>Background</h4>Effective management of patients using warfarin is resource-intensive, requiring frequent in-clinic testing of the international normalized ratio (INR). Patient self-testing (PST) using portable at-home ... -
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)BACKGROUND: Disseminated tuberculosis is a major health problem in countries where generalized human immunodeficiency virus (HIV) infection epidemics coincide with high tuberculosis incidence rates; data are limited on patient ... -
Bacterial vaginosis as a risk factor for high-grade cervical lesions and cancer in HIV-seropositive women.
(Int J Gynaecol Obstet, 2011-09)OBJECTIVE: To assess the effect of bacterial vaginosis (BV) on the risk of high-grade squamous intraepithelial lesions (HSIL) among HIV-seropositive women. METHODS: A hospital-based prospective cohort study of HIV-seropositive ... -
Barriers to and facilitators of interventions to counter publication bias: thematic analysis of scholarly articles and stakeholder interviews.
(BMC Health Serv Res, 2014-11-13)BACKGROUND: When the nature and direction of research results affect their chances of publication, a distortion of the evidence base - termed publication bias - results. Despite considerable recent efforts to implement measures ... -
Can acute clinical outcomes predict health-related quality of life after stroke: a one-year prospective study of stroke survivors.
(Health and quality of life outcomes, 2018-11-21)<h4>Background</h4>Health-related quality of life (HRQoL) is a key metric to understand the impact of stroke from patients' perspective. Yet HRQoL is not readily measured in clinical practice. This study aims to investigate ... -
Can caregivers report their care recipients' post-stroke hospitalizations and outpatient visits accurately? Findings of an Asian prospective stroke cohort.
(BMC health services research, 2018-10-25)<h4>Background</h4>Health services research aimed at understanding service use and improving resource allocation often relies on collecting subjectively reported or proxy-reported healthcare service utilization (HSU) data. ... -
Can we understand population healthcare needs using electronic medical records?
(Singapore medical journal, 2019-09)<h4>Introduction</h4>The identification of population-level healthcare needs using hospital electronic medical records (EMRs) is a promising approach for the evaluation and development of tailored healthcare services. Population ... -
Characteristics of abdominal vein thrombosis in children and adults.
(Thromb Haemost, 2013-04)The demographic and clinical characteristics of adults and children with lower extremity deep-vein thrombosis and/or pulmonary embolism (LE DVT/PE) may differ from those with abdominal vein thrombosis (abdominal VT). Abdominal ... -
Cherenkov emissions for studying tumor changes during radiation therapy: An exploratory study in domesticated dogs with naturally-occurring cancer.
(PloS one, 2020-01)<h4>Purpose</h4>Real-time monitoring of physiological changes of tumor tissue during radiation therapy (RT) could improve therapeutic efficacy and predict therapeutic outcomes. Cherenkov radiation is a normal byproduct of ...
