Browsing by Subject "Prospective Studies"
Now showing items 1-20 of 73
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A prospective comparison of a noninvasive cardiac output monitor versus esophageal Doppler monitor for goal-directed fluid therapy in colorectal surgery patients.
(Anesth Analg, 2014-05)BACKGROUND: Goal-directed fluid therapy (GDFT) is associated with improved outcomes after surgery. The esophageal Doppler monitor (EDM) is widely used, but has several limitations. The NICOM, a completely noninvasive cardiac ... -
A Randomized Phase II Crossover Study of Imatinib or Rituximab for Cutaneous Sclerosis after Hematopoietic Cell Transplantation.
(Clin Cancer Res, 2016-01-15)PURPOSE: Cutaneous sclerosis occurs in 20% of patients with chronic graft-versus-host disease (GVHD) and can compromise mobility and quality of life. EXPERIMENTAL DESIGN: We conducted a prospective, multicenter, randomized, ... -
AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings.
(Clin Infect Dis, 2010-11-01)AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection has not been adequately studied and poses unique therapeutic challenges in resource‐limited settings. Itraconazole poorly penetrates ... -
An evaluation of physician predictions of discharge on a general medicine service.
(J Hosp Med, 2015-12)The goal of this study was to evaluate general medicine physicians' ability to predict hospital discharge. We prospectively asked study subjects to predict whether each patient under their care would be discharged on the ... -
Are tuberculosis patients adherent to prescribed treatments in China? Results of a prospective cohort study.
(Infect Dis Poverty, 2016-05-05)BACKGROUND: Tuberculosis (TB) patients face numerous difficulties adhering to the long-term, rigorous TB treatment regimen. Findings on TB patients' treatment adherence vary across existing literature and official reports. ... -
Association of anxiety and depression with all-cause mortality in individuals with coronary heart disease.
(J Am Heart Assoc, 2013-03-19)BACKGROUND: Depression has been related to mortality in coronary heart disease (CHD) patients, but few studies have evaluated the role of anxiety or the role of the co-occurrence of depression and anxiety. We examined whether ... -
Bacteremic disseminated tuberculosis in sub-saharan Africa: a prospective cohort study.
(Clin Infect Dis, 2012-07)BACKGROUND: Disseminated tuberculosis is a major health problem in countries where generalized human immunodeficiency virus (HIV) infection epidemics coincide with high tuberculosis incidence rates; data are limited on patient ... -
Bacterial vaginosis as a risk factor for high-grade cervical lesions and cancer in HIV-seropositive women.
(Int J Gynaecol Obstet, 2011-09)OBJECTIVE: To assess the effect of bacterial vaginosis (BV) on the risk of high-grade squamous intraepithelial lesions (HSIL) among HIV-seropositive women. METHODS: A hospital-based prospective cohort study of HIV-seropositive ... -
Barriers to and facilitators of interventions to counter publication bias: thematic analysis of scholarly articles and stakeholder interviews.
(BMC Health Serv Res, 2014-11-13)BACKGROUND: When the nature and direction of research results affect their chances of publication, a distortion of the evidence base - termed publication bias - results. Despite considerable recent efforts to implement measures ... -
Childhood bullying involvement predicts low-grade systemic inflammation into adulthood.
(Proc Natl Acad Sci U S A, 2014-05-27)Bullying is a common childhood experience that involves repeated mistreatment to improve or maintain one's status. Victims display long-term social, psychological, and health consequences, whereas bullies display minimal ... -
Chronic Lyme disease: the controversies and the science.
(Expert Rev Anti Infect Ther, 2011-07)The diagnosis of chronic Lyme disease has been embroiled in controversy for many years. This is exacerbated by the lack of a clinical or microbiologic definition, and the commonality of chronic symptoms in the general population. ... -
Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes.
(Neurology, 2016-01-12)OBJECTIVE: To compare the performance of formal prognostic instruments vs subjective clinical judgment with regards to predicting functional outcome in patients with spontaneous intracerebral hemorrhage (ICH). METHODS: This ... -
Creatinine- versus cystatin C-based renal function assessment in the Northern Manhattan Study.
(PloS one, 2018-01)BACKGROUND:Accurate glomerular filtration rate estimation informs drug dosing and risk stratification. Body composition heterogeneity influences creatinine production and the precision of creatinine-based estimated glomerular ... -
Cumulative early life adversity predicts longevity in wild baboons.
(Nat Commun, 2016-04-19)In humans and other animals, harsh circumstances in early life predict morbidity and mortality in adulthood. Multiple adverse conditions are thought to be especially toxic, but this hypothesis has rarely been tested in a ... -
Downstream coronary effects of drug-eluting stents.
(Am Heart J, 2011-10)BACKGROUND: Antiproliferative agents used in drug-eluting stents (DES) attenuate atherosclerosis, yet DES implantation has been linked to endothelial dysfunction. The downstream effects of DES on new lesion formation have ... -
Durability of antiretroviral therapy and predictors of virologic failure among perinatally HIV-infected children in Tanzania: a four-year follow-up.
(BMC Infect Dis, 2014-11-07)BACKGROUND: In Tanzania, HIV-1 RNA testing is rarely available and not standard of care. Determining virologic failure is challenging and resistance mutations accumulate, thereby compromising second-line therapy. We evaluated ... -
Early-life soy exposure and age at menarche.
(Paediatr Perinat Epidemiol, 2012-03)This study examines the timing of menarche in relation to infant-feeding methods, specifically addressing the potential effects of soy isoflavone exposure through soy-based infant feeding. Subjects were participants in the ... -
Effect of genetic testing for risk of type 2 diabetes mellitus on health behaviors and outcomes: study rationale, development and design.
(BMC Health Serv Res, 2012-01-18)BACKGROUND: Type 2 diabetes is a prevalent chronic condition globally that results in extensive morbidity, decreased quality of life, and increased health services utilization. Lifestyle changes can prevent the development ... -
Effect of obesity on B-type natriuretic peptide levels in patients with pulmonary arterial hypertension.
(Am J Cardiol, 2012-09-15)Brain natriuretic peptide (BNP) levels are lower in obese patients with left ventricular failure than in their comparably ill, leaner counterparts. The effect of obesity on BNP in patients with pulmonary arterial hypertension ... -
Electrocardiographic J Wave and Cardiovascular Outcomes in the General Population (from the Atherosclerosis Risk In Communities Study).
(Am J Cardiol, 2016-09-15)The association between the J wave, a key component of the early repolarization pattern, and adverse cardiovascular outcomes remains unclear. Inconsistencies have stemmed from the different methods used to measure the J ...
