Browsing by Subject "Prostate cancer"
Now showing items 1-6 of 6
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Dietary Carbohydrate Restriction Slows Prostate Tumor Growth
(2008)Glucose metabolism remains an intensely explored topic of cancer biology since the initial discoveries of Otto Warburg nearly 80 years ago. Many solid tumors metabolize glucose primarily to lactate despite the availability ... -
Patterns of inpatient care for prostate cancer in men with spina bifida.
(Disability and health journal, 2020-04)BACKGROUND:Advances in medical care have increased the long-term survival of patients with spina bifida. Despite this growing population, limited knowledge is available on age-related illnesses in adults with spina bifida, ... -
Targeting androgen receptor-independent pathways in therapy-resistant prostate cancer.
(Asian journal of urology, 2019-01)Since androgen receptor (AR) signaling is critically required for the development of prostate cancer (PCa), targeting AR axis has been the standard treatment of choice for advanced and metastatic PCa. Unfortunately, although ... -
Targeting Histone Deacetylases in Advanced Prostate Cancer
(2015)The androgen receptor (AR) signaling axis is a well-established therapeutic target in prostate cancer, due to its central role in tumor maintenance and progression. Although patients respond initially to androgen deprivation ... -
The Roles of Rap1 in Cancer Metastasis and Pancreatic Islet Beta Cell Function
(2009)Signaling from the G protein, Rap1 is involved in several fundamental biological processes. Yet the mechanism or even consequence of Rap1 signaling in several biologies and diseases is still unclear. Rap1 has been implicated ... -
Thermally-Responsive Biopolymer Depots for the Delivery of High-Dose, β-Radionuclide Brachytherapy in the Treatment of Prostate and Pancreatic Cancer
(2018)Intratumoral radiation therapy – ‘brachytherapy’ – is a highly effective treatment for solid tumors, particularly prostate cancer. Current titanium seed implants, however, are permanent and are limited in clinical application ...