Now showing items 1-2 of 2

    • Phosphorylation at tyrosine 262 promotes GADD34 protein turnover. 

      Jeyaraman, Krishna; Shenolikar, Shirish; Yusoff, Permeen; Zhou, Wei (The Journal of biological chemistry, 2013-11)
      In mammalian cells, metabolic and environmental stress increases the phosphorylation of the eukaryotic translational initiation factor, eIF2α, and attenuates global protein synthesis. Subsequent transcriptional activation ...
    • The inoculum effect and band-pass bacterial response to periodic antibiotic treatment. 

      Kuehn, Margarethe Joanna; Prasada, S; Riccione, KA; Smith, RP; Srimani, JK; Tan, C; You, L (Mol Syst Biol, 2012)
      The inoculum effect (IE) refers to the decreasing efficacy of an antibiotic with increasing bacterial density. It represents a unique strategy of antibiotic tolerance and it can complicate design of effective antibiotic ...