Now showing items 1-2 of 2

    • Across the meiotic divide - CSF activity in the post-Emi2/XErp1 era. 

      Wu, JQ; Kornbluth, S (J Cell Sci, 2008-11-01)
      Vertebrate eggs are arrested at the metaphase stage of meiosis II. Only upon fertilization will the metaphase-II-arrested eggs exit meiosis II and enter interphase. In 1971, Masui and Markert injected egg extracts into a ...
    • Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. 

      Freel, CD; Guo, Y; Hansen, DV; Jackson, PK; Kornbluth, S; Tang, W; Tung, Jeffrey J; ... (9 authors) (Proc Natl Acad Sci U S A, 2007-10-16)
      Before fertilization, vertebrate eggs are arrested in meiosis II by cytostatic factor (CSF), which holds the anaphase-promoting complex (APC) in an inactive state. It was recently reported that Mos, an integral component ...