Browsing by Subject "Pseudomonas aeruginosa"
Now showing items 1-6 of 6
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Bloodstream infections in community hospitals in the 21st century: a multicenter cohort study.
(PLoS One, 2014)BACKGROUND: While the majority of healthcare in the US is provided in community hospitals, the epidemiology and treatment of bloodstream infections in this setting is unknown. METHODS AND FINDINGS: We undertook this multicenter, ... -
Characterizing Stress-Induced Outer Membrane Vesicle Production in Pseudomonas aeruginosa
(2013)As an opportunistic Gram-negative pathogen, Pseudomonas aeruginosa must be able to adapt to changes and survive stressors in its environment during the course of infection. To aid survival in the hostile host environment, ... -
Drug design from the cryptic inhibitor envelope.
(Nat Commun, 2016-02-25)Conformational dynamics plays an important role in enzyme catalysis, allosteric regulation of protein functions and assembly of macromolecular complexes. Despite these well-established roles, such information has yet to ... -
Interactions of a secreted Pseudomonas aeruginosa aminopeptidase with bacterial outer membrane molecules: characterization and implications for bacterial pathogenic phenotypes.
(2017-05-08)The protein Pseudomonas aeruginosa aminopeptidase (PaAP) is secreted by the opportunistic, Gram-negative bacterial pathogen Pseudomonas aeruginosa. PaAP expression appears to be upregulated in clinical isolates of P. aeruginosa, ... -
Stress-induced outer membrane vesicle production by Pseudomonas aeruginosa.
(J Bacteriol, 2013-07)As an opportunistic Gram-negative pathogen, Pseudomonas aeruginosa must be able to adapt and survive changes and stressors in its environment during the course of infection. To aid survival in the hostile host environment, ... -
SulA inhibits assembly of FtsZ by a simple sequestration mechanism.
(Biochemistry, 2012-04)We have investigated the inhibition by SulA of the assembly of Escherichia coli FtsZ. Using quantitative GTPase and fluorescence assays, we found that SulA inhibition resulted in an increase in the apparent critical concentration ...
