Browsing by Subject "Quality of Life"
Now showing items 1-20 of 47
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A new instrument for measuring anticoagulation-related quality of life: development and preliminary validation.
(Health Qual Life Outcomes, 2004-05-06)BACKGROUND: Anticoagulation can reduce quality of life, and different models of anticoagulation management might have different impacts on satisfaction with this component of medical care. Yet, to our knowledge, there are ... -
A systematic review of reviews: exploring the relationship between obesity, weight loss and health-related quality of life.
(Clinical obesity, 2017-10)This is the first systematic review of reviews to assess the effect of obesity and weight loss on health-related quality of life (HRQoL). We identified 12 meta-analyses/systematic reviews published between January 2001 and ... -
Can acute clinical outcomes predict health-related quality of life after stroke: a one-year prospective study of stroke survivors.
(Health and quality of life outcomes, 2018-11-21)<h4>Background</h4>Health-related quality of life (HRQoL) is a key metric to understand the impact of stroke from patients' perspective. Yet HRQoL is not readily measured in clinical practice. This study aims to investigate ... -
Childhood maltreatment and impact on clinical features of major depression in adults.
(Psychiatry research, 2020-11)<h4>Objectives</h4>This study examined: 1) the prevalence of childhood maltreatment (CMT) in individuals with chronic and/or recurrent depression, 2) the association between CMT and depressive symptoms, 3) the link between ... -
Clinical research challenges posed by difficult-to-treat depression.
(Psychological medicine, 2022-02)Approximately one-third of individuals in a major depressive episode will not achieve sustained remission despite multiple, well-delivered treatments. These patients experience prolonged suffering and disproportionately ... -
Cohort Profile: Panel on Health and Ageing of Singaporean Elderly (PHASE).
(International journal of epidemiology, 2019-12) -
Colchicine effectiveness in symptom and inflammation modification in knee osteoarthritis (COLKOA): study protocol for a randomized controlled trial.
(Trials, 2015-04-30)BACKGROUND: Despite the high prevalence and global impact of knee osteoarthritis (KOA), current treatments are palliative. No disease modifying anti-osteoarthritic drug (DMOAD) has been approved. We recently demonstrated ... -
Depression, Functional Dependence, Quality of Life and Return to Work Among Hospitalized Burn Patients in Wuhan, China
(2019)Burn injuries are devastating in both the acute and chronic phases. Survivors face life-lasting effects from such injuries, often decreasing general health, quality of life and employment status. With increased survival ... -
Design of the Healthcare Worker Exposure Response and Outcomes (HERO) research platform.
(Contemporary clinical trials, 2021-10)<h4>Background</h4>The SARS CoV-2 virus has caused one of the deadliest pandemics in recent history, resulting in over 170 million deaths and global economic disruption. There remains an urgent need for clinical trials to ... -
Development of a clinical trials version of the Impact of Weight on Quality of Life-Lite questionnaire (IWQOL-Lite Clinical Trials Version): results from two qualitative studies.
(Clinical obesity, 2017-10)Existing measures of health-related quality of life and patient functioning in obesity, such as the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire, lack the developmental rigour required by the Food ... -
Do healthcare needs-based population segments predict outcomes among the elderly? Findings from a prospective cohort study in an urbanized low-income community.
(BMC geriatrics, 2020-02-27)<h4>Background</h4>A rapidly ageing population with increasing prevalence of chronic disease presents policymakers the urgent task of tailoring healthcare services to optimally meet changing needs. While healthcare needs-based ... -
Effects of the dietary approaches to stop hypertension diet, exercise, and caloric restriction on neurocognition in overweight adults with high blood pressure.
(Hypertension, 2010-06)High blood pressure increases the risks of stroke, dementia, and neurocognitive dysfunction. Although aerobic exercise and dietary modifications have been shown to reduce blood pressure, no randomized trials have examined ... -
Explaining rural/non-rural disparities in physical health-related quality of life: a study of United Methodist clergy in North Carolina.
(Qual Life Res, 2011-08)PURPOSE: Researchers have documented lower health-related quality of life (HRQL) in rural areas. This study seeks to identify factors that can explain this disparity. METHODS: United Methodist clergy in North Carolina (N = 1,513) ... -
Extended-release ranolazine: critical evaluation of its use in stable angina.
(Vasc Health Risk Manag, 2011)Coronary heart disease is the major cause of morbidity and mortality throughout the world, and is responsible for approximately one of every six deaths in the US. Angina pectoris is a clinical syndrome characterized ... -
Health-related quality of life loss associated with first-time stroke.
(PloS one, 2019-01-28)OBJECTIVES:This study aimed to quantify health-related quality of life (HRQoL) loss associated with first episode of stroke by comparing patient-reported HRQoL before and after stroke onset. The impact of stroke in local ... -
Heart failure with preserved ejection fraction: New approaches to diagnosis and management.
(Clinical cardiology, 2020-02)The majority of older patients who develop heart failure (HF), particularly older women, have a preserved left ventricular ejection fraction (HFpEF). Patients with HFpEF have severe symptoms of exercise intolerance, poor ... -
How do prescription opioid users differ from users of heroin or other drugs in psychopathology: results from the National Epidemiologic Survey on Alcohol and Related Conditions.
(Journal of addiction medicine, 2011-03)To study substance use and psychiatric disorders among prescription opioid users, heroin users, and non-opioid drug users in a national sample of adults.Analyses of data from the 2001-2002 National Epidemiologic Survey on ... -
Identifying treatment effects of an informal caregiver education intervention to increase days in the community and decrease caregiver distress: a machine-learning secondary analysis of subgroup effects in the HI-FIVES randomized clinical trial.
(Trials, 2020-02)<h4>Background</h4>Informal caregivers report substantial burden and depressive symptoms which predict higher rates of patient institutionalization. While caregiver education interventions may reduce caregiver distress and ... -
Improving implementation of evidence-based therapies for heart failure.
(Clinical cardiology, 2022-06)Treatment options for patients with heart failure have improved rapidly over the last few decades. Data from large scale clinical trials demonstrate that medical and device therapies can improve quality of life, ... -
Living with long-term consequences: Experience of follow-up care and support needs among Asian long-term colorectal cancer survivors.
(Psycho-oncology, 2020-10)<h4>Objectives</h4>This study aimed to provide an in-depth exploration of follow-up care experiences and supportive care needs in long-term colorectal cancer (CRC) survivors within multiethnic Asian communities.<h4>Metho...
