Browsing by Subject "RNAi"
Now showing items 1-5 of 5
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Dengue Virus Host Factors
(2009)Dengue fever and dengue hemorrhagic fever are estimated to afflict 50-100 million people annually and are caused by one of the four serotypes of dengue virus. Dengue virus is carried and transmitted to humans by mosquitoes ... -
Genetic Analysis of the Contribution of Ion Channels to "Drosophila" Nociception
(2012)<p>Nociceptors are specialized primary sensory neurons that represent the first line of defense against potentially tissue damaging environmental stimuli, and are involved in pathological pain states caused by nerve damage, ... -
Genome evolution in the fungal pathogen Cryptococcus deuterogattii
(2017)One of the key challenges of the 21st century is the emergence and reemergence of pathogens. Fungal pathogens represent an important portion of this problem, as the cohort of immunocompromised patients susceptible to common ... -
Roles of RNA interference and DNA mismatch repair in maintaining genomic integrity in Cryptococcus pathogens
(2022)Microorganisms must regulate genomic stability to strike a balance between excessive deleterious mutation and evolutionary stagnation to successfully compete and endure within their ecological niches. Two important mechanisms ... -
Unisexual Reproduction in Cryptococcus: Evolutionary Implications, Virulence and RNA Silencing
(2013)Sexual development enables microbial pathogens to purge deleterious mutations from the genome and drives genetic diversity in the population. <italic>Cryptococcus neoformans</italic> is a human fungal pathogen with a defined ...
