Browsing by Subject "Receptor, Angiotensin, Type 1"
Now showing items 1-3 of 3
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beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking.
(Proc Natl Acad Sci U S A, 2001-02-13)The two widely coexpressed isoforms of beta-arrestin (termed beta arrestin 1 and 2) are highly similar in amino acid sequence. The beta-arrestins bind phosphorylated heptahelical receptors to desensitize and target them ... -
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity.
(Proc Natl Acad Sci U S A, 2000-02-01)Recently, we identified a GTPase-activating protein for the ADP ribosylation factor family of small GTP-binding proteins that we call GIT1. This protein initially was identified as an interacting partner for the G protein-coupled ... -
When 7 transmembrane receptors are not G protein-coupled receptors.
(J Clin Invest, 2005-11)Classically, 7 transmembrane receptors transduce extracellular signals by coupling to heterotrimeric G proteins, although recent in vitro studies have clearly demonstrated that they can also signal via G protein-independent ...
