Browsing by Subject "Receptors, CCR5"
Now showing items 1-8 of 8
-
A cell-based multiplex immunoassay platform using fluorescent protein-barcoded reporter cell lines.
(Communications biology, 2021-11)Multiplex immunoassays with acellular antigens are well-established based on solid-phase platforms such as the Luminex® technology. Cell barcoding by amine-reactive fluorescent dyes enables analogous cell-based multiplex ... -
Anti-phospholipid human monoclonal antibodies inhibit CCR5-tropic HIV-1 and induce beta-chemokines.
(J Exp Med, 2010-04-12)Traditional antibody-mediated neutralization of HIV-1 infection is thought to result from the binding of antibodies to virions, thus preventing virus entry. However, antibodies that broadly neutralize HIV-1 are rare and ... -
Chlamydia trachomatis Infection of Endocervical Epithelial Cells Enhances Early HIV Transmission Events.
(PloS one, 2016-01)Chlamydia trachomatis causes a predominantly asymptomatic, but generally inflammatory, genital infection that is associated with an increased risk for HIV acquisition. Endocervical epithelial cells provide the major niche ... -
Determinants of protection among HIV‐exposed seronegative persons: an overview.
(J Infect Dis, 2010-11-01)Both clinical experience and a growing medical literature indicate that some persons who have been exposed to human immunodeficiency virus (HIV) infection remain uninfected. Although in some instances this may represent ... -
Effects of three long-acting reversible contraceptive methods on HIV target cells in the human uterine cervix and peripheral blood.
(Reproductive biology and endocrinology : RB&E, 2019-02)<h4>Background</h4>Hormonal contraceptives, particularly depot medroxyprogesterone acetate (DMPA), have been reported to be associated with substantially enhanced HIV acquisition; however, the biological mechanisms of this ... -
Hematopoietic cell transplantation with cord blood for cure of HIV infections.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2013-03)Hematopoietic cell transplantation (HCT) using CCR5-Δ32/Δ32 stem cells from an adult donor has resulted in the only known cure of human immunodeficiency virus (HIV) infection. However, it is not feasible to repeat this procedure ... -
Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing.
(J Virol, 2011-03)HIV transmission via breastfeeding accounts for a considerable proportion of infant HIV acquisition. However, the origin and evolution of the virus population in breast milk, the likely reservoir of transmitted virus variants, ... -
Reliable genotypic tropism tests for the major HIV-1 subtypes.
(Scientific reports, 2015-02-25)Over the past decade antiretroviral drugs have dramatically improved the prognosis for HIV-1 infected individuals, yet achieving better access to vulnerable populations remains a challenge. The principal obstacle to the ...
