ALERT: This system is being upgraded on Tuesday December 12. It will not be available for use for several hours that day while the upgrade is in progress. Deposits to DukeSpace will be disabled on Monday December 11, so no new items are to be added to the repository while the upgrade is in progress. Everything should be back to normal by the end of day, December 12.

Now showing items 1-3 of 3

    • Functional evolution of mammalian odorant receptors. 

      Adipietro, Kaylin Alexis (2012)
      The ability to detect small volatile molecules in the environment is mediated by the large repertoire of odorant receptors (ORs) in each species. The mammalian OR repertoire is an attractive model to study evolution because ...
    • Olfactory Receptor Subgenomes Linked with Broad Ecological Adaptations in Sauropsida. 

      Khan, Imran; Yang, Zhikai; Maldonado, Emanuel; Li, Cai; Zhang, Guojie; Gilbert, M Thomas P; Jarvis, Erich D; ... (10 authors) (Mol Biol Evol, 2015-11)
      Olfactory receptors (ORs) govern a prime sensory function. Extant birds have distinct olfactory abilities, but the molecular mechanisms underlining diversification and specialization remain mostly unknown. We explored OR ...
    • The missense of smell: functional variability in the human odorant receptor repertoire. 

      Mainland, Joel D; Keller, Andreas; Li, Yun R; Zhou, Ting; Trimmer, Casey; Snyder, Lindsey L; Moberly, Andrew H; ... (14 authors) (Nat Neurosci, 2014-01)
      Humans have ~400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms ...