Now showing items 1-5 of 5

    • Antibiotic overuse for acute respiratory tract infections in Sri Lanka: a qualitative study of outpatients and their physicians. 

      Tillekeratne, L Gayani; Bodinayake, Champica K; Dabrera, Thushani; Nagahawatte, Ajith; Arachchi, Wasantha Kodikara; Sooriyaarachchi, Anoji; Stewart, Kearsley; ... (10 authors) (BMC Fam Pract, 2018-03-01)
      BACKGROUND: Acute respiratory tract infections (ARTIs) are a common reason for antibiotic overuse worldwide. We previously showed that over 80% of outpatients presenting to a tertiary care hospital in Sri Lanka ...
    • Host gene expression classifiers diagnose acute respiratory illness etiology. 

      Tsalik, Ephraim L; Henao, Ricardo; Nichols, Marshall; Burke, Thomas; Ko, Emily R; McClain, Micah T; Hudson, Lori L; ... (24 authors) (Sci Transl Med, 2016-01-20)
      Acute respiratory infections caused by bacterial or viral pathogens are among the most common reasons for seeking medical care. Despite improvements in pathogen-based diagnostics, most patients receive inappropriate antibiotics. ...
    • Host-Based Diagnostics for Acute Respiratory Infections. 

      Ross, Melissa H; Zick, Brittany L; Tsalik, Ephraim L (Clinical therapeutics, 2019-10)
      PURPOSE:The inappropriate use of antimicrobials, especially in acute respiratory infections (ARIs), is largely driven by difficulty distinguishing bacterial, viral, and noninfectious etiologies of illness. A new frontier ...
    • Maternal Effects of Respiratory Syncytial Virus Infection during Pregnancy. 

      Wheeler, Sarahn M; Dotters-Katz, Sarah; Heine, R Phillip; Grotegut, Chad A; Swamy, Geeta K (Emerg Infect Dis, 2015-11)
      Given the illness and deaths caused by respiratory syncytial virus (RSV) infection during the first year of life, preventing infant RSV infections through maternal vaccination is intriguing. However, little is known about ...
    • The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood. 

      Tsalik, Ephraim L; Fiorino, Cassandra; Aqeel, Ammara; Liu, Yiling; Henao, Ricardo; Ko, Emily R; Burke, Thomas W; ... (18 authors) (Frontiers in immunology, 2021-01)
      Viruses cause a wide spectrum of clinical disease, the majority being acute respiratory infections (ARI). In most cases, ARI symptoms are similar for different viruses although severity can be variable. The objective of ...