Now showing items 1-2 of 2

    • Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A. 

      Freel, CD; Guo, Y; Hansen, DV; Jackson, PK; Kornbluth, S; Tang, W; Tung, Jeffrey J; ... (9 authors) (Proc Natl Acad Sci U S A, 2007-10-16)
      Before fertilization, vertebrate eggs are arrested in meiosis II by cytostatic factor (CSF), which holds the anaphase-promoting complex (APC) in an inactive state. It was recently reported that Mos, an integral component ...
    • Suppression of DNA-damage checkpoint signaling by Rsk-mediated phosphorylation of Mre11. 

      Chen, C; Zhang, L; Huang, NJ; Huang, B; Kornbluth, S (Proc Natl Acad Sci U S A, 2013-12-17)
      Ataxia telangiectasia mutant (ATM) is an S/T-Q-directed kinase that is critical for the cellular response to double-stranded breaks (DSBs) in DNA. Following DNA damage, ATM is activated and recruited by the MRN protein complex ...