Now showing items 1-2 of 2

    • Defects in intracellular trafficking of fungal cell wall synthases lead to aberrant host immune recognition. 

      Alspaugh, James; Esher, Shannon K; Ost, Kyla S; Kohlbrenner, Maria A; Pianalto, Kaila M; Telzrow, Calla L; Campuzano, Althea; ... (10 authors) (PLoS pathogens, 2018-06-04)
      The human fungal pathogen, Cryptococcus neoformans, dramatically alters its cell wall, both in size and composition, upon entering the host. This cell wall remodeling is essential for host immune avoidance by this pathogen. ...
    • HDAC genes play distinct and redundant roles in Cryptococcus neoformans virulence. 

      Alspaugh, James; Brandão, Fabiana; Esher, Shannon K; Ost, Kyla S; Pianalto, Kaila; Nichols, Connie B; Fernandes, Larissa; ... (9 authors) (Scientific reports, 2018-03-26)
      The human fungal pathogen Cryptococcus neoformans undergoes many phenotypic changes to promote its survival in specific ecological niches and inside the host. To explore the role of chromatin remodeling on the expression ...