Browsing by Subject "SARS-CoV-2"

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Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction.

Katsura, Hiroaki; Sontake, Vishwaraj; Tata, Aleksandra; Kobayashi, Yoshihiko; Edwards, Caitlin E; Heaton, Brook E; Konkimalla, Arvind; ... (16 authors) (Cell stem cell, 2020-10-21)

Coronavirus infection causes diffuse alveolar damage leading to acute respiratory distress syndrome. The absence of ex vivo models of human alveolar epithelium is hindering an understanding of coronavirus disease 2019 (COVID-19) ...
Positive selection within the genomes of SARS-CoV-2 and other Coronaviruses independent of impact on protein function.

Berrio, Alejandro; Gartner, Valerie; Wray, Gregory A (PeerJ, 2020-01)

Background:The emergence of a novel coronavirus (SARS-CoV-2) associated with severe acute respiratory disease (COVID-19) has prompted efforts to understand the genetic basis for its unique characteristics and its jump from ...