Browsing by Subject "Siblings"
Now showing items 1-8 of 8
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Ethical considerations of using a single minor donor for three bone marrow harvests for three HLA-matched siblings with primary immunodeficiency.
(Pediatric blood & cancer, 2019-04)Allogeneic hematopoietic stem cell transplantation is curative for primary immunodeficiencies. Bone marrow from an unaffected human leukocyte antigen (HLA)-identical sibling donor is the ideal graft source. For minor donors, ... -
Family-directed umbilical cord blood banking.
(Haematologica, 2011-11)Umbilical cord blood transplantation from HLA-identical siblings provides good results in children. These results support targeted efforts to bank family cord blood units that can be used for a sibling diagnosed with a disease ... -
Fanny Hensel, Felix Mendelssohn Bartholdy, and the Formation of the "Mendelssohnian" Style
(2013)Fanny Hensel wrote much of Felix Mendelssohn's music. Or so goes the popular misconception. It is true that Felix did publish six of his sister's Lieder under his own name, in his Op. 8 and Op. 9, but there is no evidence ... -
Genome-wide linkage analysis for human longevity: Genetics of Healthy Aging Study.
(Aging Cell, 2013-04)Clear evidence exists for heritability of human longevity, and much interest is focused on identifying genes associated with longer lives. To identify such longevity alleles, we performed the largest genome-wide linkage ... -
Low tobacco-related cancer incidence in offspring of long-lived siblings: a comparison with Danish national cancer registry data.
(Ann Epidemiol, 2015-08)PURPOSE: Familial clustering of longevity is well documented and includes both genetic and other familial factors, but the specific underlying mechanisms are largely unknown. We examined whether low incidence of specific ... -
Myeloablative transplantation using either cord blood or bone marrow leads to immune recovery, high long-term donor chimerism and excellent survival in chronic granulomatous disease.
(Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2012-09)The curative potential of hematopoietic stem cell transplantation in patients with chronic granulomatous disease depends on availability of a suitable donor, successful donor engraftment, and maintenance of long-term donor ... -
Sickle cell disease: an international survey of results of HLA-identical sibling hematopoietic stem cell transplantation.
(Blood, 2017-03)Despite advances in supportive therapy to prevent complications of sickle cell disease (SCD), access to care is not universal. Hematopoietic cell transplantation is, to date, the only curative therapy for SCD, but its application ... -
The influence of stem cell source on transplant outcomes for pediatric patients with acute myeloid leukemia.
(Blood advances, 2019-04)When hematopoietic stem cell transplant (HSCT) is necessary for children with acute myeloid leukemia (AML), there remains debate about the best stem cell source. Post-HSCT relapse is a common cause of mortality, and complications ...
