Now showing items 1-5 of 5

    • A beta-adrenergic receptor kinase-like enzyme is involved in olfactory signal termination. 

      Schleicher, S; Boekhoff, I; Arriza, J; Lefkowitz, RJ; Breer, H (Proc Natl Acad Sci U S A, 1993-02-15)
      We have previously shown that second-messenger-dependent kinases (cAMP-dependent kinase, protein kinase C) in the olfactory system are essential in terminating second-messenger signaling in response to odorants. We now document ...
    • A Functionally Conserved Gene Regulatory Network Module Governing Olfactory Neuron Diversity. 

      Li, Qingyun; Barish, Scott; Okuwa, Sumie; Maciejewski, Abigail; Brandt, Alicia T; Reinhold, Dominik; Jones, Corbin D; ... (8 authors) (PLoS Genet, 2016-01)
      Sensory neuron diversity is required for organisms to decipher complex environmental cues. In Drosophila, the olfactory environment is detected by 50 different olfactory receptor neuron (ORN) classes that are clustered in ...
    • Decoding an olfactory mechanism of kin recognition and inbreeding avoidance in a primate. 

      Boulet, Marylène; Charpentier, Marie JE; Drea, Christine M (BMC Evol Biol, 2009-12-03)
      BACKGROUND: Like other vertebrates, primates recognize their relatives, primarily to minimize inbreeding, but also to facilitate nepotism. Although associative, social learning is typically credited for discrimination of ...
    • Olfactory cuing of autobiographical memory. 

      Rubin, DC; Groth, E; Goldsmith, DJ (Am J Psychol, 1984)
      In Experiment 1, subjects were presented with either the odors or the names of 15 common objects. In Experiment 2, subjects were presented with either the odors, photographs, or names of 16 common objects. All subjects were ...
    • The missense of smell: functional variability in the human odorant receptor repertoire. 

      Mainland, Joel D; Keller, Andreas; Li, Yun R; Zhou, Ting; Trimmer, Casey; Snyder, Lindsey L; Moberly, Andrew H; ... (14 authors) (Nat Neurosci, 2014-01)
      Humans have ~400 intact odorant receptors, but each individual has a unique set of genetic variations that lead to variation in olfactory perception. We used a heterologous assay to determine how often genetic polymorphisms ...