Browsing by Subject "Synthetic biology"
Now showing items 1-5 of 5
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A Synthetic-biology Approach to Understanding Bacterial Programmed Death and Implications for Antibiotic Treatment
(2013)Programmed death is often associated with a bacterial stress response. This behavior appears paradoxical, as it offers no benefit to the individual. This paradox can be explained if the death is `altruistic': the sacrifice ... -
Enabling Technologies for Synthetic Biology: Gene Synthesis and Error-Correction from a Microarray-Microfluidic Integrated Device
(2011)Promising applications in the design of various biological systems hold critical implications as heralded in the rising field of synthetic biology. But, to achieve these goals, the ability to synthesize in situ DNA constructs ... -
Genetic Assembly, Error-Correction and a High-Throughput Screening Strategy for Protein Expression Optimization
(2012)Various types of genetic constructs are widely used as diagnostic, prophylactic, and therapeutic tools for human diseases. They are also the workhorse in biotech and pharmaceutical industry for production of therapeutic ... -
Intrinsically Disordered Protein Polymer Libraries as Tools to Understand Protein Hydrophobicity
(2019)Intrinsically disordered protein polymers (IDPPs) are repetitive biopolymers that, when enriched with prolines, glycines, and aliphatic amino acids, have observable lower critical solution temperature (LCST) phase transition ... -
Quantifying and Inhibiting Horizontal Gene Transfer-Mediated Antibiotic Resistance
(2017)Antibiotic discovery and widespread usage has revolutionized the treatment of infectious diseases. However, this golden age of modern-day medicine is threatened by the increasing prevalence of antibiotic-resistant pathogens. ...
